TY - JOUR
T1 - Clinical report on the treatment of locally advanced lung cancer
AU - Petrovich, Zbigniew
AU - Mietlowski, William
AU - Ohanian, Maimu
AU - Cox, James
PY - 1977/7
Y1 - 1977/7
N2 - This paper discusses the results of the treatment of 345 patients entered in the Veterans Administration Lung Group Protocol 13L. The study was activated March 1972, and closed for the patient accesion March 1975. All patients had a histological diagnosis of primary lung cancer considered clinically non‐resec‐table or inoperable. Patients were equally randomized into two groups, radiotherapy alone or radiotherapy with chemotherapy. The analysis of the data included: treatment regimen, radiation dose, initial performance status, performance status change, cell type, duration of survival, quality of survival and age. The strongest influence on median survival was the level of radiation dose. The small cell carcinoma patients treated with radiotherapy and chemotherapy showed significant improvement in the median survival (38.2 weeks) over the patients treated with radiotherapy alone (20.6 weeks). The patients treated with radiotherapy and chemotherapy also showed improvement in performance status more frequently than the patients treated with radiotherapy alone. Other parameters of the analysis will be presented. Cancer 40:72–77, 1977.
AB - This paper discusses the results of the treatment of 345 patients entered in the Veterans Administration Lung Group Protocol 13L. The study was activated March 1972, and closed for the patient accesion March 1975. All patients had a histological diagnosis of primary lung cancer considered clinically non‐resec‐table or inoperable. Patients were equally randomized into two groups, radiotherapy alone or radiotherapy with chemotherapy. The analysis of the data included: treatment regimen, radiation dose, initial performance status, performance status change, cell type, duration of survival, quality of survival and age. The strongest influence on median survival was the level of radiation dose. The small cell carcinoma patients treated with radiotherapy and chemotherapy showed significant improvement in the median survival (38.2 weeks) over the patients treated with radiotherapy alone (20.6 weeks). The patients treated with radiotherapy and chemotherapy also showed improvement in performance status more frequently than the patients treated with radiotherapy alone. Other parameters of the analysis will be presented. Cancer 40:72–77, 1977.
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U2 - 10.1002/1097-0142(197707)40:1<72::AID-CNCR2820400114>3.0.CO;2-Q
DO - 10.1002/1097-0142(197707)40:1<72::AID-CNCR2820400114>3.0.CO;2-Q
M3 - Article
C2 - 195709
AN - SCOPUS:0017692625
SN - 0008-543X
VL - 40
SP - 72
EP - 77
JO - Cancer
JF - Cancer
IS - 1
ER -