Combating resistance to anti-IGFR antibody by targeting the integrin β3-Src pathway

Medicine & Life Sciences

• anti-IGF-1R antibody A12 100%
• Somatomedin Receptors 50%
• Integrins 48%
• Anti-Idiotypic Antibodies 43%
• Squamous Cell Carcinoma of Head and Neck 21%
• Insulin-Like Growth Factor I 19%
• Non-Small Cell Lung Carcinoma 17%
• Nude Mice 12%
• Confidence Intervals 11%
• Cell Line 11%
• Small Interfering RNA 10%
• Immunoprecipitation 6%
• Tumor Burden 6%
• Cell Adhesion 5%
• Drug Resistance 5%
• Heterografts 5%
• In Vitro Techniques 5%
• Fluorescent Antibody Technique 5%
• Analysis of Variance 5%
• Signal Transduction 4%
• Monoclonal Antibodies 4%
• Ligands 4%
• Enzyme-Linked Immunosorbent Assay 4%
• Students 4%
• Western Blotting 4%
• Neoplasms 4%
• Therapeutics 2%