TY - JOUR
T1 - Comparative cytologic and histologic study of fifteen salivary basal- cell tumors
T2 - Differential diagnostic considerations
AU - Klijanienko, Jerzy
AU - El-Naggar, Adel K.
AU - Vielh, Philippe
N1 - Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 1999/7
Y1 - 1999/7
N2 - Cytologic results of preoperative fine-needle sampling (FNS) of 15 salivary basal-cell tumors are presented, described, and compared with histologic results. Eleven of the FNAS showed individual and clusters of homogeneous basaloid cells with scanty cytoplasm, occasional peripheral palisading, and naked nuclei and were diagnosed as basal-cell adenoma. Four samples showed, in addition, three-dimensional cell clusters with mild cytonuclear atypia, occasional mitosis, and/or focal necrosis and were diagnosed as basal-cell adenocarcinoma. Basal-cell tumors must be diagnostically differentiated from adenoid cystic carcinoma and metastatic basal-cell carcinoma. Although the adenomas diagnosed by cytologic examination and four suspected carcinomas in our series were verified by histologic testing, the bland cytologic features of basal-cell adenocarcinoma may not always allow diagnosis on cytologic examination.
AB - Cytologic results of preoperative fine-needle sampling (FNS) of 15 salivary basal-cell tumors are presented, described, and compared with histologic results. Eleven of the FNAS showed individual and clusters of homogeneous basaloid cells with scanty cytoplasm, occasional peripheral palisading, and naked nuclei and were diagnosed as basal-cell adenoma. Four samples showed, in addition, three-dimensional cell clusters with mild cytonuclear atypia, occasional mitosis, and/or focal necrosis and were diagnosed as basal-cell adenocarcinoma. Basal-cell tumors must be diagnostically differentiated from adenoid cystic carcinoma and metastatic basal-cell carcinoma. Although the adenomas diagnosed by cytologic examination and four suspected carcinomas in our series were verified by histologic testing, the bland cytologic features of basal-cell adenocarcinoma may not always allow diagnosis on cytologic examination.
KW - Basal-cell adenocarcinoma
KW - Basal-cell adenoma
KW - Cytology
KW - Fine-needle sampling
KW - Salivary glands
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U2 - 10.1002/(SICI)1097-0339(199907)21:1<30::AID-DC9>3.0.CO;2-9
DO - 10.1002/(SICI)1097-0339(199907)21:1<30::AID-DC9>3.0.CO;2-9
M3 - Article
C2 - 10405805
AN - SCOPUS:0032976837
SN - 8755-1039
VL - 21
SP - 30
EP - 34
JO - Diagnostic Cytopathology
JF - Diagnostic Cytopathology
IS - 1
ER -