@article{1b8552f661bd40b892255b7543e28722,
title = "Comparative in vitro pharmacodynamic analysis of isavuconazole, voriconazole, and posaconazole against clinical isolates of aspergillosis, mucormycosis, fusariosis, and phaeohyphomycosis",
abstract = "We compared the in vitro pharmacodynamics of isavuconazole, voriconazole, and posaconazole against 92 clinical isolates from documented cases of invasive aspergillosis, mucormycosis, fusariosis, and phaeohyphomycosis. Whereas inhibitory and fungicidal concentrations of these triazoles were predictably similar with the exception of Mucorales, isavuconazole appeared to have improved pharmacodynamics against Fusarium solani.",
keywords = "Antifungal therapy, Fusariosis, Isavuconazole, Mold pathogens, Mucormycosis, Pharmacodynamics",
author = "Lewis, {Russell E.} and Sebastian Wurster and Beyda, {Nicholas D.} and Albert, {Nathaniel D.} and Kontoyiannis, {Dimitrios P.}",
note = "Funding Information: DPK acknowledges the Texas 4000 Distinguished Professorship for Cancer Research and the NIH-NCI Cancer Center CORE Support grant no. 16672. REL has received research support from Merck & Co and has served on advisory boards for Astellas Pharma and Cidara Therapeutics. NDB has received research support from and is on the advisory board of Astellas Pharma. DPK reports research support from Astellas Pharma and honoraria from Merck & Co, Amplyx Pharmaceuticals, Astellas Pharma, Gilead Sciences, Cidara Therapeutics, and Mayne Pharmaceuticals. He has served as a consultant for Astellas Pharma, Merck & Co, and Pfizer. All other authors report no potential conflicts of interest. Funding Information: DPK acknowledges the Texas 4000 Distinguished Professorship for Cancer Research and the NIH-NCI Cancer Center CORE Support grant no. 16672 . Funding Information: This project was funded by an investigator-initiated proposal by Astellas Inc. to DPK. The sponsor had no role in the design or performance of experiments, data interpretation, or preparation of this manuscript. Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",
year = "2019",
month = nov,
doi = "10.1016/j.diagmicrobio.2019.06.013",
language = "English (US)",
volume = "95",
journal = "Diagnostic Microbiology and Infectious Disease",
issn = "0732-8893",
publisher = "Elsevier Inc.",
number = "3",
}