Abstract
Introduction: The purpose of our study was to compare the performance of 2D (FFDM) against 3D (FFDM plus DBT) examinations in the post-treatment surveillance of asymptomatic breast cancer survivors. Methods: A list of women with a history of breast cancer who underwent screening mammography (2D or 3D) from 5/2017 to 5/2020 was retrieved. A total of 20,210 examinations were identified and performance metrics were compared. Results: There were no statistically significant difference in cancer detection rate (CDR) (p = 0.38), recall rate (RR) (p = 0.087), or positive predictive value (PPV) (p = 0.74) between 2D vs. 3D examinations. Stratification by breast tissue identified no statistically significant difference in CDR (p = 0.581 and p = 0.428), RR (p = 0.230 and p = 0.205), or PPV (p = 0.908 and p = 0.721) between fatty/scattered and heterogeneous/extremely dense breast tissue when comparing 2D vs 3D examinations. Stratification by age did not identify a significant difference in RR or PPV between the two groups. CDR was statistically increased with 2D vs. 3D examinations in the 60–69 years group (p = 0.021). Stratification by race did not identify a significant difference in RR or PPV between the two groups. CDR was statistically increased with 3D vs. 2D examinations in white women (p = 0.036). Stratification by laterality (bilateral vs. unilateral post mastectomy) did not identify a significant difference in RR or PPV between the two groups. CDR was statistically increased in 2D vs. 3D examinations in unilateral studies (p = 0.009). Conclusion: For asymptomatic women with a history of breast cancer, there is no evidence that the addition of DBT to FFDM improves CDR, RR, or PPV. Implications for practice: More studies are needed concerning screening methodologies supplementing FFDM in the screening regimens of breast cancer survivors.
Original language | English (US) |
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Pages (from-to) | 975-979 |
Number of pages | 5 |
Journal | Radiography |
Volume | 29 |
Issue number | 6 |
DOIs | |
State | Published - Oct 2023 |
Keywords
- 2D mammography
- 3D mammography
- Breast cancer
- Breast cancer survivor
- Tomosynthesis
ASJC Scopus subject areas
- Research and Theory
- Radiological and Ultrasound Technology
- Health Professions (miscellaneous)
- Radiology Nuclear Medicine and imaging
- Assessment and Diagnosis
MD Anderson CCSG core facilities
- Biostatistics Resource Group