TY - JOUR
T1 - Comparison of indoor air quality between 2 ventilation strategies in a facility housing rhesus macaques (Macaca mulatta)
AU - De Oca, Nicole A.Monts
AU - Laughlin, Mitzi
AU - Jenkins, John
AU - Lockworth, Cynthia R.
AU - Bolton, Iris D.
AU - Brammer, David W.
N1 - Publisher Copyright:
Copyright © 2015 by the American Association for Laboratory Animal Science.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - Adequate indoor-air quality (IAQ)-defined by the temperature, relative humidity, and the levels of carbon dioxide, small particles, and total volatile organic compounds (TVOC)-is crucial in laboratory animal facilities. The ventilation standards for controlling these parameters are not well defined. This study assessed the effect of 2 ventilation strategies on IAQ in 2 rooms housing rhesus macaques (Macaca mulatta). We hypothesized that using a demand-controlled ventilation (DCV) system with a baseline ventilation rate of less than 3 fresh-air changes per hour (ACH) would maintain IAQ comparable to or better than the traditional constant flow rate (CFR) system at 12 fresh ACH. During a 60-d study period, each of the 2 rooms operated 30 d on DCV and 30 d on CFR ventilation. In both rooms, temperatures remained more consistently within the established setpoint during the DCV phase than during the CFR phase. Relative humidity did not differ significantly between rooms or strategies. CO2 was lower during the CFR phase than DCV phase. Small-particle and TVOC levels were lower during CFR in the larger (3060 ft3) room but not the smaller (2340 ft3) room. During the DCV phase, the larger room was at the baseline airflow rate over 99% of the time and the smaller room over 96% of the time. The DCV strategy resulted in a baseline airflow rate of less than 3 ACH, which in turn provided acceptable IAQ over 96% of the time; higher ventilation rates were warranted only during sanitation periods.
AB - Adequate indoor-air quality (IAQ)-defined by the temperature, relative humidity, and the levels of carbon dioxide, small particles, and total volatile organic compounds (TVOC)-is crucial in laboratory animal facilities. The ventilation standards for controlling these parameters are not well defined. This study assessed the effect of 2 ventilation strategies on IAQ in 2 rooms housing rhesus macaques (Macaca mulatta). We hypothesized that using a demand-controlled ventilation (DCV) system with a baseline ventilation rate of less than 3 fresh-air changes per hour (ACH) would maintain IAQ comparable to or better than the traditional constant flow rate (CFR) system at 12 fresh ACH. During a 60-d study period, each of the 2 rooms operated 30 d on DCV and 30 d on CFR ventilation. In both rooms, temperatures remained more consistently within the established setpoint during the DCV phase than during the CFR phase. Relative humidity did not differ significantly between rooms or strategies. CO2 was lower during the CFR phase than DCV phase. Small-particle and TVOC levels were lower during CFR in the larger (3060 ft3) room but not the smaller (2340 ft3) room. During the DCV phase, the larger room was at the baseline airflow rate over 99% of the time and the smaller room over 96% of the time. The DCV strategy resulted in a baseline airflow rate of less than 3 ACH, which in turn provided acceptable IAQ over 96% of the time; higher ventilation rates were warranted only during sanitation periods.
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M3 - Article
C2 - 26424251
AN - SCOPUS:84943194215
SN - 1559-6109
VL - 54
SP - 527
EP - 535
JO - Journal of the American Association for Laboratory Animal Science
JF - Journal of the American Association for Laboratory Animal Science
IS - 5
ER -