Comparison of results of salvage therapy in adult acute myelogenous leukemia

Michael J. Keating; Elihu Estey; Hagop M. Kantarjian; Ronald Walters; Terry Smith; Kenneth B. McCredie; Emil J. Freireich

doi:10.1159/000205916

Comparison of results of salvage therapy in adult acute myelogenous leukemia

Michael J. Keating, Elihu Estey, Hagop M. Kantarjian, Ronald Walters, Terry Smith, Kenneth B. McCredie, Emil J. Freireich

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The results of initial salvage therapy for refractory and relapsed acute myelogenous leukemia for patients treated between 1973 and 1986 have been evaluated. There was no significant improvement in complete remission (CR) rate and survival in patients treated between 1973 and 1980, and the second group between 1981 and 1986. The remission duration was slightly longer in the second time period than in the initial time period. A number of factors were associated with the probability of achieving a CR. The major factors were the age of the patient, duration of the initial CR, liver function test abnormalities, and white blood cell count.

Original language	English (US)
Pages (from-to)	120-126
Number of pages	7
Journal	Acta haematologica
Volume	78
DOIs	https://doi.org/10.1159/000205916
State	Published - 1987

Keywords

Acute myeloid leukemia
Prediction response
Salvage treatment

ASJC Scopus subject areas

Hematology

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10.1159/000205916

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title = "Comparison of results of salvage therapy in adult acute myelogenous leukemia",

abstract = "The results of initial salvage therapy for refractory and relapsed acute myelogenous leukemia for patients treated between 1973 and 1986 have been evaluated. There was no significant improvement in complete remission (CR) rate and survival in patients treated between 1973 and 1980, and the second group between 1981 and 1986. The remission duration was slightly longer in the second time period than in the initial time period. A number of factors were associated with the probability of achieving a CR. The major factors were the age of the patient, duration of the initial CR, liver function test abnormalities, and white blood cell count.",

keywords = "Acute myeloid leukemia, Prediction response, Salvage treatment",

author = "Keating, {Michael J.} and Elihu Estey and Kantarjian, {Hagop M.} and Ronald Walters and Terry Smith and McCredie, {Kenneth B.} and Freireich, {Emil J.}",

year = "1987",

doi = "10.1159/000205916",

language = "English (US)",

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pages = "120--126",

journal = "Acta haematologica",

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T1 - Comparison of results of salvage therapy in adult acute myelogenous leukemia

AU - Keating, Michael J.

AU - Estey, Elihu

AU - Kantarjian, Hagop M.

AU - Walters, Ronald

AU - Smith, Terry

AU - McCredie, Kenneth B.

AU - Freireich, Emil J.

PY - 1987

Y1 - 1987

N2 - The results of initial salvage therapy for refractory and relapsed acute myelogenous leukemia for patients treated between 1973 and 1986 have been evaluated. There was no significant improvement in complete remission (CR) rate and survival in patients treated between 1973 and 1980, and the second group between 1981 and 1986. The remission duration was slightly longer in the second time period than in the initial time period. A number of factors were associated with the probability of achieving a CR. The major factors were the age of the patient, duration of the initial CR, liver function test abnormalities, and white blood cell count.

AB - The results of initial salvage therapy for refractory and relapsed acute myelogenous leukemia for patients treated between 1973 and 1986 have been evaluated. There was no significant improvement in complete remission (CR) rate and survival in patients treated between 1973 and 1980, and the second group between 1981 and 1986. The remission duration was slightly longer in the second time period than in the initial time period. A number of factors were associated with the probability of achieving a CR. The major factors were the age of the patient, duration of the initial CR, liver function test abnormalities, and white blood cell count.

KW - Acute myeloid leukemia

KW - Prediction response

KW - Salvage treatment

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SP - 120

EP - 126

JO - Acta haematologica

JF - Acta haematologica

ER -

Comparison of results of salvage therapy in adult acute myelogenous leukemia

Abstract

Keywords

ASJC Scopus subject areas

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