Compensation for spin-lock artifacts using an off-resonance rotary echo in T1ρoff-weighted imaging

Walter R.T. Witschey; Arijitt Borthakur; Mark A. Elliott; Eric Mellon; Sampreet Niyogi; Chenyang Wang; Ravinder Reddy

doi:10.1002/mrm.21134

Compensation for spin-lock artifacts using an off-resonance rotary echo in T_1ρoff-weighted imaging

Walter R.T. Witschey, Arijitt Borthakur, Mark A. Elliott, Eric Mellon, Sampreet Niyogi, Chenyang Wang, Ravinder Reddy

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

The origin of image artifacts in an off-resonance spin-locking experiment is shown to be imperfections in the excitation flip angle. A pulse sequence for off-resonance spin locking is implemented that compensates for imperfections in the excitation flip angle through an off-resonance rotary echo. The off-resonance rotary echo alternates the frequency offset and phase of the RF transmitter during two spin-locking pulses of equal duration. The underlying theory is detailed, and MR images demonstrate the effectiveness of the technique in agarose gel phantoms and in in vivo human brain at 3T.

Original language	English (US)
Pages (from-to)	2-7
Number of pages	6
Journal	Magnetic resonance in medicine
Volume	57
Issue number	1
DOIs	https://doi.org/10.1002/mrm.21134
State	Published - Jan 2007
Externally published	Yes

Keywords

Off-resonance T
Rotary echo
Spin locking
T relaxation
T-weighted imaging

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1002/mrm.21134

Cite this

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title = "Compensation for spin-lock artifacts using an off-resonance rotary echo in T1ρoff-weighted imaging",

abstract = "The origin of image artifacts in an off-resonance spin-locking experiment is shown to be imperfections in the excitation flip angle. A pulse sequence for off-resonance spin locking is implemented that compensates for imperfections in the excitation flip angle through an off-resonance rotary echo. The off-resonance rotary echo alternates the frequency offset and phase of the RF transmitter during two spin-locking pulses of equal duration. The underlying theory is detailed, and MR images demonstrate the effectiveness of the technique in agarose gel phantoms and in in vivo human brain at 3T.",

keywords = "Off-resonance T, Rotary echo, Spin locking, T relaxation, T-weighted imaging",

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T1 - Compensation for spin-lock artifacts using an off-resonance rotary echo in T1ρoff-weighted imaging

AU - Witschey, Walter R.T.

AU - Borthakur, Arijitt

AU - Elliott, Mark A.

AU - Mellon, Eric

AU - Niyogi, Sampreet

AU - Wang, Chenyang

AU - Reddy, Ravinder

PY - 2007/1

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AB - The origin of image artifacts in an off-resonance spin-locking experiment is shown to be imperfections in the excitation flip angle. A pulse sequence for off-resonance spin locking is implemented that compensates for imperfections in the excitation flip angle through an off-resonance rotary echo. The off-resonance rotary echo alternates the frequency offset and phase of the RF transmitter during two spin-locking pulses of equal duration. The underlying theory is detailed, and MR images demonstrate the effectiveness of the technique in agarose gel phantoms and in in vivo human brain at 3T.

KW - Off-resonance T

KW - Rotary echo

KW - Spin locking

KW - T relaxation

KW - T-weighted imaging

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