Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells

Robin M. Meyers, Jordan G. Bryan, James M. McFarland, Barbara A. Weir, Ann E. Sizemore, Han Xu, Neekesh V. Dharia, Phillip G. Montgomery, Glenn S. Cowley, Sasha Pantel, Amy Goodale, Yenarae Lee, Levi D. Ali, Guozhi Jiang, Rakela Lubonja, William F. Harrington, Matthew Strickland, Ting Wu, Derek C. Hawes, Victor A. ZhivichMeghan R. Wyatt, Zohra Kalani, Jaime J. Chang, Michael Okamoto, Kimberly Stegmaier, Todd R. Golub, Jesse S. Boehm, Francisca Vazquez, David E. Root, William C. Hahn, Aviad Tsherniak

Research output: Contribution to journal › Article › peer-review

1047 Scopus citations

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Medicine & Life Sciences