Abstract
OBJECTIVE: To evaluate the performance of a computer-aided detection (CAD) system for diagnosis of pulmonary embolism on computed tomography (CT) pulmonary angiography. MATERIALS AND METHODS: One hundred and four pulmonary CT angiograms for pulmonary emboli (PE) were reviewed both by radiologists and a CAD detection system (ImageChecker CT V2.0, R2 Technology Inc, Sunnyvale, CA). CT scans, read and reported by radiologists in a routine daily clinical setting, were later processed by the CAD system. The performance of the CAD system was analyzed. RESULTS: Forty-five PE were identified by the radiologists in 15 patients. The CAD system revealed 123 findings, interpreted by the system as PE. Twenty-six of them, detected in 8 patients, represented true-positive results. Ninety-seven (78.9%) CAD findings were not true PE and were defined as false-positive. Nineteen true PE in 7 patients were missed by the CAD system constituting 42% false-negative rate. Sensitivity of the CAD system was 53.3% and the specificity was 77.5%. The positive predictive value of CAD system was 28.5% and the negative predictive value was 90.7%. CONCLUSIONS: With the evaluated CAD system, it is relatively simple and fast to check all detected findings and decide if they represent true PE. However, high false-negative results demand technologic improvement, to increase the sensitivity of the system. It is anticipated to become a promising supplement to the work and eyes of the radiologist in detecting PE on pulmonary CT angiography.
Original language | English (US) |
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Pages (from-to) | 324-329 |
Number of pages | 6 |
Journal | Journal of Thoracic Imaging |
Volume | 22 |
Issue number | 4 |
DOIs | |
State | Published - Nov 2007 |
Externally published | Yes |
Keywords
- Computer-aided detection
- Pulmonary CT angiography
- Pulmonary embolism
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Pulmonary and Respiratory Medicine