Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia

Kensuke Kojima, Marina Konopleva, Twee Tsao, Hideki Nakakuma, Michael Andreeff

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Fingerprint

Dive into the research topics of 'Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia'. Together they form a unique fingerprint.

Medicine & Life Sciences

Chemistry