Concurrent Chemo-radiation As a Means of Achieving Pathologic Complete Response in Triple Negative Breast Cancer

Maryam Nemati Shafaee, Shalini Makawita, Bora Lim, Matthew J. Ellis, Michelle S. Ludwig

Research output: Contribution to journalComment/debatepeer-review

Abstract

Management of triple negative breast cancer (TNBC) that is resistant to chemotherapy remains a challenge. Many studies have investigated the unconventional approach of concurrent chemotherapy with radiation in management of TNBC that is resistant to neoadjuvant anthracycline and taxane containing chemotherapy. Various chemotherapies have been used as radiosensitizers. In this report we summarize the published literature and highlight clinical trials that pertain to management of TNBC.

Original languageEnglish (US)
Pages (from-to)e536-e543
JournalClinical breast cancer
Volume22
Issue number4
DOIs
StatePublished - Jun 2022
Externally publishedYes

Keywords

  • Concurrent Chemo-radiation
  • Pathologic complete response
  • Primary resistant TNBC
  • Triple negative breast cancer

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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