Continuous-infusion vinblastine in refractory carcinoma of the cervix: A phase II trial

John J. Kavanagh; Larry J. Copeland; David M. Gershenson; Patton B. Saul; J. Taylor Wharton; Felix N. Rutledge

doi:10.1016/0090-8258(85)90254-9

Continuous-infusion vinblastine in refractory carcinoma of the cervix: A phase II trial

John J. Kavanagh, Larry J. Copeland, David M. Gershenson, Patton B. Saul, J. Taylor Wharton, Felix N. Rutledge

Gynecological Oncology & Reproductive Medicine

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Twenty patients with recurrent or metastatic squamous cell carcinoma of the cervix were treated with continuous-infusion vinblastine sulfate. Two patients (10%) had partial responses of 4 and 7 months' duration. Neutropenia was dose limiting. Vinblastine sulfate given by continuous infusion has limited activity in this malignancy.

Original language	English (US)
Pages (from-to)	211-214
Number of pages	4
Journal	Gynecologic oncology
Volume	21
Issue number	2
DOIs	https://doi.org/10.1016/0090-8258(85)90254-9
State	Published - Jun 1985

ASJC Scopus subject areas

Oncology
Obstetrics and Gynecology

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title = "Continuous-infusion vinblastine in refractory carcinoma of the cervix: A phase II trial",

abstract = "Twenty patients with recurrent or metastatic squamous cell carcinoma of the cervix were treated with continuous-infusion vinblastine sulfate. Two patients (10%) had partial responses of 4 and 7 months' duration. Neutropenia was dose limiting. Vinblastine sulfate given by continuous infusion has limited activity in this malignancy.",

author = "Kavanagh, {John J.} and Copeland, {Larry J.} and Gershenson, {David M.} and Saul, {Patton B.} and Wharton, {J. Taylor} and Rutledge, {Felix N.}",

year = "1985",

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AU - Kavanagh, John J.

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AU - Gershenson, David M.

AU - Saul, Patton B.

AU - Wharton, J. Taylor

AU - Rutledge, Felix N.

PY - 1985/6

Y1 - 1985/6

N2 - Twenty patients with recurrent or metastatic squamous cell carcinoma of the cervix were treated with continuous-infusion vinblastine sulfate. Two patients (10%) had partial responses of 4 and 7 months' duration. Neutropenia was dose limiting. Vinblastine sulfate given by continuous infusion has limited activity in this malignancy.

AB - Twenty patients with recurrent or metastatic squamous cell carcinoma of the cervix were treated with continuous-infusion vinblastine sulfate. Two patients (10%) had partial responses of 4 and 7 months' duration. Neutropenia was dose limiting. Vinblastine sulfate given by continuous infusion has limited activity in this malignancy.

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Continuous-infusion vinblastine in refractory carcinoma of the cervix: A phase II trial

Abstract

ASJC Scopus subject areas

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