Continuous sc infusion of narcotics using a portable disposable device in patients with advanced cancer

E. Bruera, C. Brenneis, M. Michaud, S. Chadwick, R. N. MacDonald

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Fifty-six patients with chronic pain due to advanced cancer were treated with an sc infusion of morphone (34 patients) or hydromorphone (22 patients) using a portable disposable infusor. The infusion was maintained for 26 ± 14 days. Twenty-five patients (45%) were discharged to the home for a mean period of 18 days (range, 2-138). The mean daily increase in dose was 2.6% ± 1.4% of the initial dose. The sc site needed to be changed every 8 days (range, 2-31). Local toxicity consisted of infection in two patients (3%), chemical irritation in three (5%), and bleeding in one (2%). After 48 hours of treatment, 54 of 56 patients (96%) preferred the sc infusion to their previous parenteral treatment. We conclude that this is a safe and simple method for the administration of narcotics to inpatients and outpatients.

Original languageEnglish (US)
Pages (from-to)635-637
Number of pages3
JournalCancer Treatment Reports
Volume71
Issue number6
StatePublished - 1987
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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