Corticosteroid therapy for liver abscess in chronic granulomatous disease

Jennifer W. Leiding; Alexandra F. Freeman; Beatriz E. Marciano; Victoria L. Anderson; Gulbu Uzel; Harry L. Malech; Suksee Deravin; David Wilks; Aradhana M. Venkatesan; Christa S. Zerbe; Theo Heller; Steven M. Holland

doi:10.1093/cid/cir896

Corticosteroid therapy for liver abscess in chronic granulomatous disease

Jennifer W. Leiding, Alexandra F. Freeman, Beatriz E. Marciano, Victoria L. Anderson, Gulbu Uzel, Harry L. Malech, Suksee Deravin, David Wilks, Aradhana M. Venkatesan, Christa S. Zerbe, Theo Heller, Steven M. Holland

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Abstract

Liver abscesses in chronic granulomatous disease (CGD) are typically difficult to treat and often require surgery. We describe 9 X-linked CGD patients with staphylococcal liver abscesses refractory to conventional therapy successfully treated with corticosteroids and antibiotics. Corticosteroids may have a role in treatment of Staphylococcus aureus liver abscesses in CGD.

Original language	English (US)
Pages (from-to)	694-700
Number of pages	7
Journal	Clinical Infectious Diseases
Volume	54
Issue number	5
DOIs	https://doi.org/10.1093/cid/cir896
State	Published - Mar 1 2012
Externally published	Yes

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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title = "Corticosteroid therapy for liver abscess in chronic granulomatous disease",

abstract = "Liver abscesses in chronic granulomatous disease (CGD) are typically difficult to treat and often require surgery. We describe 9 X-linked CGD patients with staphylococcal liver abscesses refractory to conventional therapy successfully treated with corticosteroids and antibiotics. Corticosteroids may have a role in treatment of Staphylococcus aureus liver abscesses in CGD.",

author = "Leiding, {Jennifer W.} and Freeman, {Alexandra F.} and Marciano, {Beatriz E.} and Anderson, {Victoria L.} and Gulbu Uzel and Malech, {Harry L.} and Suksee Deravin and David Wilks and Venkatesan, {Aradhana M.} and Zerbe, {Christa S.} and Theo Heller and Holland, {Steven M.}",

note = "Funding Information: Financial support. This work was supported by the Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health.",

year = "2012",

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doi = "10.1093/cid/cir896",

language = "English (US)",

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T1 - Corticosteroid therapy for liver abscess in chronic granulomatous disease

AU - Leiding, Jennifer W.

AU - Freeman, Alexandra F.

AU - Marciano, Beatriz E.

AU - Anderson, Victoria L.

AU - Uzel, Gulbu

AU - Malech, Harry L.

AU - Deravin, Suksee

AU - Wilks, David

AU - Venkatesan, Aradhana M.

AU - Zerbe, Christa S.

AU - Heller, Theo

AU - Holland, Steven M.

N1 - Funding Information: Financial support. This work was supported by the Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health.

PY - 2012/3/1

Y1 - 2012/3/1

N2 - Liver abscesses in chronic granulomatous disease (CGD) are typically difficult to treat and often require surgery. We describe 9 X-linked CGD patients with staphylococcal liver abscesses refractory to conventional therapy successfully treated with corticosteroids and antibiotics. Corticosteroids may have a role in treatment of Staphylococcus aureus liver abscesses in CGD.

AB - Liver abscesses in chronic granulomatous disease (CGD) are typically difficult to treat and often require surgery. We describe 9 X-linked CGD patients with staphylococcal liver abscesses refractory to conventional therapy successfully treated with corticosteroids and antibiotics. Corticosteroids may have a role in treatment of Staphylococcus aureus liver abscesses in CGD.

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AN - SCOPUS:84856913573

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JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

IS - 5

ER -

Corticosteroid therapy for liver abscess in chronic granulomatous disease

Abstract

ASJC Scopus subject areas

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