Critical Care of the Cancer Patient with Pulmonary Infiltrates

The first point of contact of microbial pathogens entering the lungs are the epithelial cells that line the airways and alveoli, and the lining fluid that bathes their apical surface. Lung epithelial cells constitutively Table 2 Infectious Etiologies of Pulmonary Infiltrates Associated with Specific Immune Defects: Deficiencies of Local Defenses Type of microorganism Associated conditions Bacterial Fungal Viral Mucositis Streptoccoccus spp. Aspergillus Herpes simplex Altered glottic function Staphylococcus spp. Candida Varicella-zoster Indwelling catheters Pseudomonas spp. Mucoraceae Endotracheal tubes Enterobacteriaceae Fusaria Venipunctures Corynebacterium Table 3 Infectious Etiologies of Pulmonary Infiltrates Associated with Specific Immune Defects: Deficiencies in Innate Immunity Type of microorganism Defect Associated conditions Bacterial Fungal Neutrophil disorder Neutropenia Mucositis Psuedomonas aerginosa Aspergillus Acute leukemia Staphylococcus aureus Candida Hodgkin's lymphoma Coagulase negative staphylococci Mucoraceae Tumor infiltration of BM Viridans streptococci Fusaria Infectious=infiltration of BM Enterobacteria Cryptococcus Chemotherapy Corynebacterium jeikeium Pseudoallescheria spp. Radiation therapy Enterococci Histoplasma spp.