TY - JOUR
T1 - Current treatment and management of retinoblastoma
AU - Gombos, Dan S.
AU - Chevez-Barrios, Patricia
PY - 2007/11
Y1 - 2007/11
N2 - Retinoblastoma was traditionally treated with enucleation and external-beam radiotherapy. However, in the past decade, systemic chemotherapy has become the primary globe-salvaging approach. This approach is generally combined with focal treatment, allowing for tumor consolidation following initial chemoreduction. A recently developed classification scheme may improve our ability to predict outcomes with this treatment modality. The Children's Oncology Group has initiated a series of prospective multicenter trials to improve treatment outcomes with systemic chemotherapy.
AB - Retinoblastoma was traditionally treated with enucleation and external-beam radiotherapy. However, in the past decade, systemic chemotherapy has become the primary globe-salvaging approach. This approach is generally combined with focal treatment, allowing for tumor consolidation following initial chemoreduction. A recently developed classification scheme may improve our ability to predict outcomes with this treatment modality. The Children's Oncology Group has initiated a series of prospective multicenter trials to improve treatment outcomes with systemic chemotherapy.
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U2 - 10.1007/s11912-007-0063-7
DO - 10.1007/s11912-007-0063-7
M3 - Review article
C2 - 17991352
AN - SCOPUS:36049037186
SN - 1523-3790
VL - 9
SP - 453
EP - 458
JO - Current oncology reports
JF - Current oncology reports
IS - 6
ER -