Current update on combined hepatocellular-cholangiocarcinoma

Suresh Maximin; Dhakshina Moorthy Ganeshan; Alampady K. Shanbhogue; Manjiri K. Dighe; Matthew M. Yeh; Orpheus Kolokythas; Puneet Bhargava; Neeraj Lalwani

doi:10.1016/j.ejro.2014.07.001

Current update on combined hepatocellular-cholangiocarcinoma

Suresh Maximin, Dhakshina Moorthy Ganeshan, Alampady K. Shanbhogue, Manjiri K. Dighe, Matthew M. Yeh, Orpheus Kolokythas, Puneet Bhargava, Neeraj Lalwani

Research output: Contribution to journal › Review article › peer-review

50 Scopus citations

Abstract

Combined hepatocellular-cholangiocarcinoma is a rare but unique primary hepatic tumor with characteristic histology and tumor biology.Recent development in genetics and molecular biology support the fact that combined hepatocellular-cholangiocarcinoma is closely linked withcholangiocarcinoma, rather than hepatocellular carcinoma. Combined hepatocellular cholangiocarcinoma tends to present with an more aggressive behavior and a poorer prognosis than either hepatocellularcarcinoma or cholangiocarcinoma. An accurate preoperative diagnosis and aggressive treatment planning can play crucial roles in appropriate patientmanagement.

Original language	English (US)
Pages (from-to)	40-48
Number of pages	9
Journal	European Journal of Radiology Open
Volume	1
Issue number	1
DOIs	https://doi.org/10.1016/j.ejro.2014.07.001
State	Published - 2014

Keywords

Cholangiocarcinoma
Cirrhosis
Computed tomography
Hepatocellular carcinoma
Magnetic resonance imaging

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.ejro.2014.07.001

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title = "Current update on combined hepatocellular-cholangiocarcinoma",

abstract = "Combined hepatocellular-cholangiocarcinoma is a rare but unique primary hepatic tumor with characteristic histology and tumor biology.Recent development in genetics and molecular biology support the fact that combined hepatocellular-cholangiocarcinoma is closely linked withcholangiocarcinoma, rather than hepatocellular carcinoma. Combined hepatocellular cholangiocarcinoma tends to present with an more aggressive behavior and a poorer prognosis than either hepatocellularcarcinoma or cholangiocarcinoma. An accurate preoperative diagnosis and aggressive treatment planning can play crucial roles in appropriate patientmanagement.",

keywords = "Cholangiocarcinoma, Cirrhosis, Computed tomography, Hepatocellular carcinoma, Magnetic resonance imaging",

author = "Suresh Maximin and Ganeshan, {Dhakshina Moorthy} and Shanbhogue, {Alampady K.} and Dighe, {Manjiri K.} and Yeh, {Matthew M.} and Orpheus Kolokythas and Puneet Bhargava and Neeraj Lalwani",

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AU - Maximin, Suresh

AU - Ganeshan, Dhakshina Moorthy

AU - Shanbhogue, Alampady K.

AU - Dighe, Manjiri K.

AU - Yeh, Matthew M.

AU - Kolokythas, Orpheus

AU - Bhargava, Puneet

AU - Lalwani, Neeraj

PY - 2014

Y1 - 2014

N2 - Combined hepatocellular-cholangiocarcinoma is a rare but unique primary hepatic tumor with characteristic histology and tumor biology.Recent development in genetics and molecular biology support the fact that combined hepatocellular-cholangiocarcinoma is closely linked withcholangiocarcinoma, rather than hepatocellular carcinoma. Combined hepatocellular cholangiocarcinoma tends to present with an more aggressive behavior and a poorer prognosis than either hepatocellularcarcinoma or cholangiocarcinoma. An accurate preoperative diagnosis and aggressive treatment planning can play crucial roles in appropriate patientmanagement.

AB - Combined hepatocellular-cholangiocarcinoma is a rare but unique primary hepatic tumor with characteristic histology and tumor biology.Recent development in genetics and molecular biology support the fact that combined hepatocellular-cholangiocarcinoma is closely linked withcholangiocarcinoma, rather than hepatocellular carcinoma. Combined hepatocellular cholangiocarcinoma tends to present with an more aggressive behavior and a poorer prognosis than either hepatocellularcarcinoma or cholangiocarcinoma. An accurate preoperative diagnosis and aggressive treatment planning can play crucial roles in appropriate patientmanagement.

KW - Cholangiocarcinoma

KW - Cirrhosis

KW - Computed tomography

KW - Hepatocellular carcinoma

KW - Magnetic resonance imaging

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JF - European Journal of Radiology Open

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Current update on combined hepatocellular-cholangiocarcinoma

Abstract

Keywords

ASJC Scopus subject areas

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