TY - JOUR
T1 - Cutaneous melanocytic lesions
T2 - Do not miss the invisible gorilla
AU - Prieto, Victor G.
N1 - Copyright:
Copyright 2012 Elsevier B.V., All rights reserved.
PY - 2012/7
Y1 - 2012/7
N2 - Of all pathology fields, the analysis of melanocytic lesions has one of the highest rates of review for legal reasons, particularly regarding the distinction between nevus and melanoma. Among the most frequently involved are desmoplastic melanoma, nevoid melanoma, and Spitz nevus versus spitzoid melanoma. Therefore, it follows that pathologists and dermatopathologists should pay special attention when dealing with such type of lesions. This review article will emphasize a number of clinical, histologic, and immunohistochemical features we believe are essential when evaluating lesions whose differential diagnosis includes melanoma/nevus. Furthermore, we want to stress the importance of examining the entire slide within the context of all available information in order to not miss the invisible gorilla in the slide. Regarding this apparently bizarre choice to illustrate these problems (to not miss an invisible gorilla), we request the reader to continue reading this article to find out why.
AB - Of all pathology fields, the analysis of melanocytic lesions has one of the highest rates of review for legal reasons, particularly regarding the distinction between nevus and melanoma. Among the most frequently involved are desmoplastic melanoma, nevoid melanoma, and Spitz nevus versus spitzoid melanoma. Therefore, it follows that pathologists and dermatopathologists should pay special attention when dealing with such type of lesions. This review article will emphasize a number of clinical, histologic, and immunohistochemical features we believe are essential when evaluating lesions whose differential diagnosis includes melanoma/nevus. Furthermore, we want to stress the importance of examining the entire slide within the context of all available information in order to not miss the invisible gorilla in the slide. Regarding this apparently bizarre choice to illustrate these problems (to not miss an invisible gorilla), we request the reader to continue reading this article to find out why.
KW - desmoplastic melanoma
KW - melanocytic lesions
KW - nevoid melanoma
KW - spitz nevus
KW - spitzoid melanoma
UR - http://www.scopus.com/inward/record.url?scp=84862557842&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84862557842&partnerID=8YFLogxK
U2 - 10.1097/PAP.0b013e31825c6be2
DO - 10.1097/PAP.0b013e31825c6be2
M3 - Review article
C2 - 22692289
AN - SCOPUS:84862557842
SN - 1072-4109
VL - 19
SP - 263
EP - 269
JO - Advances in anatomic pathology
JF - Advances in anatomic pathology
IS - 4
ER -