Data on the expression of CXCR3 ligands and pro-inflammatory cytokines in macrophages and CD4+ T cells after stimuli of CXCR3 ligands

Bongjun Kim, Jong Ho Lee, Won Jong Jin, Hong Hee Kim, Hyunil Ha, Zang Hee Lee

Research output: Contribution to journalArticlepeer-review

Abstract

C-X-C motif chemokine receptor 3 (CXCR3) is a G protein-coupled receptor for three ligands which are C-X-C motif chemokine 9 (CXCL9), CXCL10, and CXCL11 [1]. Previously we have reported that CXCL10 promotes pro-inflammatory cytokine expression, and forms positive feedback loop [2,3]. In the present study, we described mRNA expression of CXCL9 and CXCL11 under CXCL10 stimuli in the presence or absence of CXCR3 antagonist, JN-2 in bone marrow-derived macrophages (BMMs) and CD4+ T cells. In addition, we examined pro-inflammatory cytokine expression under CXCL9 or CXCL11 stimuli in BMMs and CD4+ T cells.

Original languageEnglish (US)
Pages (from-to)518-522
Number of pages5
JournalData in Brief
Volume18
DOIs
StatePublished - Jun 2018

Keywords

  • CXCL11
  • CXCL9
  • CXCR3
  • Cytokine

ASJC Scopus subject areas

  • General

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