TY - JOUR
T1 - Dealing with an insufficient future liver remnant
T2 - Portal vein embolization and two-stage hepatectomy
AU - Kawaguchi, Yoshikuni
AU - Lillemoe, Heather A.
AU - Vauthey, Jean Nicolas
N1 - Publisher Copyright:
© 2019 Wiley Periodicals, Inc.
PY - 2019/4/1
Y1 - 2019/4/1
N2 - Abstract: Colorectal liver metastases (CLM) are not always resectable at the time of diagnosis. An insufficient future liver remnant is a factor excluding patients from curative intent resection. To deal with this issue, two-stage hepatectomy was introduced approximately 20 years ago. It is a sequential treatment strategy for bilateral CLM, which consists of preoperative chemotherapy, portal vein embolization, and planned first and second liver resections. This study reviews current evidence supporting use of two-stage hepatectomy.
AB - Abstract: Colorectal liver metastases (CLM) are not always resectable at the time of diagnosis. An insufficient future liver remnant is a factor excluding patients from curative intent resection. To deal with this issue, two-stage hepatectomy was introduced approximately 20 years ago. It is a sequential treatment strategy for bilateral CLM, which consists of preoperative chemotherapy, portal vein embolization, and planned first and second liver resections. This study reviews current evidence supporting use of two-stage hepatectomy.
KW - colorectal liver metastasis
KW - future liver remnant
KW - portal vein embolization
KW - two-stage hepatectomy
UR - http://www.scopus.com/inward/record.url?scp=85062342088&partnerID=8YFLogxK
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U2 - 10.1002/jso.25430
DO - 10.1002/jso.25430
M3 - Review article
C2 - 30825223
AN - SCOPUS:85062342088
SN - 0022-4790
VL - 119
SP - 594
EP - 603
JO - Journal of surgical oncology
JF - Journal of surgical oncology
IS - 5
ER -