Decreased cell division of the uterine luminal epithelium of diabetic rats in response to 17β-estradiol

John L. Kirkland; Gene N. Barrett; George M. Stancel

doi:10.1210/endo-109-1-316

Decreased cell division of the uterine luminal epithelium of diabetic rats in response to 17β-estradiol

John L. Kirkland, Gene N. Barrett, George M. Stancel

Gynecological Oncology & Reproductive Medicine

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

The uterine growth response to estradiol as determined by luminal epithelial cell division was measured in euglycemic and drug induced insulin deficient rats. The results demonstrated that uterine cell division in insulin deficient rats is depressed when compared to euglycemic rats. Replacement of insulin by osmotic minipumps (Alza Corporation) in insulin deficient rats restored the level of luminal cell division to those observed in euglycemic rats.

Original language	English (US)
Pages (from-to)	316-318
Number of pages	3
Journal	Endocrinology
Volume	109
Issue number	1
DOIs	https://doi.org/10.1210/endo-109-1-316
State	Published - Jul 1981

ASJC Scopus subject areas

Endocrinology

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abstract = "The uterine growth response to estradiol as determined by luminal epithelial cell division was measured in euglycemic and drug induced insulin deficient rats. The results demonstrated that uterine cell division in insulin deficient rats is depressed when compared to euglycemic rats. Replacement of insulin by osmotic minipumps (Alza Corporation) in insulin deficient rats restored the level of luminal cell division to those observed in euglycemic rats.",

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AB - The uterine growth response to estradiol as determined by luminal epithelial cell division was measured in euglycemic and drug induced insulin deficient rats. The results demonstrated that uterine cell division in insulin deficient rats is depressed when compared to euglycemic rats. Replacement of insulin by osmotic minipumps (Alza Corporation) in insulin deficient rats restored the level of luminal cell division to those observed in euglycemic rats.

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Decreased cell division of the uterine luminal epithelium of diabetic rats in response to 17β-estradiol

Abstract

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