Des-Met carboxyl-terminally modified analogues of bombesin function as potent bombesin receptor antagonists, partial agonists, or agonists

Chemistry

• Bombesin 80%
• Partial Agonist 68%
• Agonist 50%
• Antagonist 32%
• Hydrazide 28%
• Ethyl Ester 28%
• Length 15%
• Methyl Ester 15%
• Phenyl Group 8%
• Ethyl 6%
• Amide 6%
• Substitution Reaction 5%
• Peptide 5%
• Modification 4%
• Electron Particle 4%
• Acid 3%

Medicine & Life Sciences

• Bombesin Receptors 79%
• Bombesin 71%
• 3T3 Cells 39%
• Guinea Pigs 26%
• neuromedin B 26%
• Esters 23%
• Pancreas 19%
• Amides 9%
• Acinar Cells 8%
• Electrons 6%
• Amino Acids 5%
• Peptides 4%