Detecting and treating cancer with nanotechnology

Keith B. Hartman; Lon J. Wilson; Michael G. Rosenblum

doi:10.1007/BF03256264

Detecting and treating cancer with nanotechnology

Keith B. Hartman, Lon J. Wilson, Michael G. Rosenblum

Experimental Therapeutics

Research output: Contribution to journal › Review article › peer-review

90 Scopus citations

Abstract

Nanotechnology offers many opportunities for enhanced diagnostic and therapeutic medicine against cancer and other diseases. In this review, the special properties that result from the nanoscale size of quantum dots, metal colloids, superparamagnetic iron oxide, and carbon-based nanostructures are reviewed and interpreted against a background of the structural and electronic detail that gives rise to their nanotechnologic behavior. The detection and treatment of cancer is emphasized, with special attention paid to the biologic targeting of the disease. The future of nanotechnology in cancer research and clinical practice is projected to focus on 'theranostic' nanoparticles that are both diagnostic and therapeutic by design.

Original language	English (US)
Pages (from-to)	1-14
Number of pages	14
Journal	Molecular Diagnosis and Therapy
Volume	12
Issue number	1
DOIs	https://doi.org/10.1007/BF03256264
State	Published - 2008

Keywords

Cancer, general
Diagnostics
Imaging agents, diagnostic use
Nanoparticles

ASJC Scopus subject areas

Molecular Medicine
Genetics
Pharmacology

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10.1007/BF03256264

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abstract = "Nanotechnology offers many opportunities for enhanced diagnostic and therapeutic medicine against cancer and other diseases. In this review, the special properties that result from the nanoscale size of quantum dots, metal colloids, superparamagnetic iron oxide, and carbon-based nanostructures are reviewed and interpreted against a background of the structural and electronic detail that gives rise to their nanotechnologic behavior. The detection and treatment of cancer is emphasized, with special attention paid to the biologic targeting of the disease. The future of nanotechnology in cancer research and clinical practice is projected to focus on 'theranostic' nanoparticles that are both diagnostic and therapeutic by design.",

keywords = "Cancer, general, Diagnostics, Imaging agents, diagnostic use, Nanoparticles",

author = "Hartman, {Keith B.} and Wilson, {Lon J.} and Rosenblum, {Michael G.}",

note = "Funding Information: The authors wish to thank the Robert A. Welch Foundation (grant no. C-0627 to Dr Wilson) and the Center for Biological the Environmental Nanotechnology (grant no. NSF EEC-0118007 to Drs Wilson and Hartman). Dr Hartman is a recipient of the Rice University Norman Hackerman Fellowship in Chemistry.",

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AU - Wilson, Lon J.

AU - Rosenblum, Michael G.

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Detecting and treating cancer with nanotechnology

Abstract

Keywords

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