Detection of novel oxidized phospholipid products by neutral loss scanning

Melissa K. Pulfer; Robert C. Murphy

Detection of novel oxidized phospholipid products by neutral loss scanning

Research output: Contribution to conference › Paper › peer-review

Abstract

Several new oxidized phospholipids products were detected by using Neutral loss scanning. It was observed that [M-H ₂O] ⁺ ions were produced during the MS/MS of free radical oxidized palmitoyl arachidonyl phospatidylcholine (PAPC) compounds corresponding to the addition of 1 to 6 oxygen atoms. It was found that there was a loss of neutral 183 from oxidized phosphatidylcholine lipids, due to remote site of proton attachment to the phosphodiester group. The results show that chain shortened products in ozonated phospholipids can be detected from the neutral loss scans for 53 to 183.

Original language	English (US)
Pages	569-570
Number of pages	2
State	Published - 2002
Externally published	Yes
Event	Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States Duration: Jun 2 2002 → Jun 6 2002

Conference

Conference	Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
Country/Territory	United States
City	Orlando, FL
Period	6/2/02 → 6/6/02

ASJC Scopus subject areas

Spectroscopy

Cite this

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title = "Detection of novel oxidized phospholipid products by neutral loss scanning",

abstract = "Several new oxidized phospholipids products were detected by using Neutral loss scanning. It was observed that [M-H 2O] + ions were produced during the MS/MS of free radical oxidized palmitoyl arachidonyl phospatidylcholine (PAPC) compounds corresponding to the addition of 1 to 6 oxygen atoms. It was found that there was a loss of neutral 183 from oxidized phosphatidylcholine lipids, due to remote site of proton attachment to the phosphodiester group. The results show that chain shortened products in ozonated phospholipids can be detected from the neutral loss scans for 53 to 183.",

author = "Pulfer, {Melissa K.} and Murphy, {Robert C.}",

year = "2002",

language = "English (US)",

pages = "569--570",

}

TY - CONF

T1 - Detection of novel oxidized phospholipid products by neutral loss scanning

AU - Pulfer, Melissa K.

AU - Murphy, Robert C.

PY - 2002

Y1 - 2002

N2 - Several new oxidized phospholipids products were detected by using Neutral loss scanning. It was observed that [M-H 2O] + ions were produced during the MS/MS of free radical oxidized palmitoyl arachidonyl phospatidylcholine (PAPC) compounds corresponding to the addition of 1 to 6 oxygen atoms. It was found that there was a loss of neutral 183 from oxidized phosphatidylcholine lipids, due to remote site of proton attachment to the phosphodiester group. The results show that chain shortened products in ozonated phospholipids can be detected from the neutral loss scans for 53 to 183.

AB - Several new oxidized phospholipids products were detected by using Neutral loss scanning. It was observed that [M-H 2O] + ions were produced during the MS/MS of free radical oxidized palmitoyl arachidonyl phospatidylcholine (PAPC) compounds corresponding to the addition of 1 to 6 oxygen atoms. It was found that there was a loss of neutral 183 from oxidized phosphatidylcholine lipids, due to remote site of proton attachment to the phosphodiester group. The results show that chain shortened products in ozonated phospholipids can be detected from the neutral loss scans for 53 to 183.

UR - http://www.scopus.com/inward/record.url?scp=2442663165&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=2442663165&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:2442663165

SP - 569

EP - 570

T2 - Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics

Y2 - 2 June 2002 through 6 June 2002

ER -

Detection of novel oxidized phospholipid products by neutral loss scanning

Abstract

Conference

ASJC Scopus subject areas

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