TY - JOUR
T1 - Determining Adequate Margins in Head and Neck Cancers
T2 - Practice and Continued Challenges
AU - Williams, Michelle D.
N1 - Publisher Copyright:
© 2016, Springer Science+Business Media New York.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Margin assessment remains a critical component of oncologic care for head and neck cancer patients. As an integrated team, both surgeons and pathologists work together to assess margins in these complex patients. Differences in method of margin sampling can impact obtainable information and effect outcomes. Additionally, what distance is an “adequate or clear” margin for patient care continues to be debated. Ultimately, future studies and potentially secondary modalities to augment pathologic assessment of margin assessment (i.e., in situ imaging or molecular assessment) may enhance local control in head and neck cancer patients.
AB - Margin assessment remains a critical component of oncologic care for head and neck cancer patients. As an integrated team, both surgeons and pathologists work together to assess margins in these complex patients. Differences in method of margin sampling can impact obtainable information and effect outcomes. Additionally, what distance is an “adequate or clear” margin for patient care continues to be debated. Ultimately, future studies and potentially secondary modalities to augment pathologic assessment of margin assessment (i.e., in situ imaging or molecular assessment) may enhance local control in head and neck cancer patients.
KW - Adequacy of resection
KW - Frozen sections
KW - Intraoperative consultation
KW - Margins
KW - NCCN
KW - Oral
KW - Pathologic assessment
KW - Squamous cell carcinoma
KW - Tongue
UR - http://www.scopus.com/inward/record.url?scp=84979742811&partnerID=8YFLogxK
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U2 - 10.1007/s11912-016-0540-y
DO - 10.1007/s11912-016-0540-y
M3 - Review article
C2 - 27469263
AN - SCOPUS:84979742811
SN - 1523-3790
VL - 18
JO - Current oncology reports
JF - Current oncology reports
IS - 9
M1 - 54
ER -