Development and validation of the simplified Chinese version of EORTC QLQ-H&N35 for patients with head and neck cancer

Zheng Yang; Qiong Meng; Jiahong Luo; Qian Lu; Xiaojiang Li; Gaofeng Li; Chonghua Wan

doi:10.1007/s00520-011-1247-0

Development and validation of the simplified Chinese version of EORTC QLQ-H&N35 for patients with head and neck cancer

Zheng Yang, Qiong Meng, Jiahong Luo, Qian Lu, Xiaojiang Li, Gaofeng Li, Chonghua Wan

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Goals A simplified Chinese version of EORTC QLQH& N35 was developed using strict translation procedures according to EORTC translation guidelines. Psychometric properties were evaluated. Patients and methods Three instruments (QLQ-H&N35, QLICP-HN, and FACT-H&N) were used in a sample of 133 patients with head and neck cancer at the time of their admission to the hospital. Each patient was assessed for the second time 1-2 days after hospitalization so that the test-retest reliability could be calculated. A sub-sample of patients was sampled and measured for the third time at discharge in order to evaluate the responsiveness. Results Correlation analysis among domains and items of the three instruments showed good construct validity and criterion-related validity. Comparisons of QLQ-H&N35 between treatment groups and age groups supported clinical validity. The internal consistency reliability measured by Cronbach's coefficient ? was greater than 0.70 for all multiitem domains, and test-retest reliability coefficients for all domains were greater than 0.80, ranging from 0.88 to 0.95. Score changes between pre- and post-treatment were observed in 6 out of 18 domains, with effect size SRM ranging from 0.27 to 0.87. Conclusions The simplified Chinese version of QLQH& N35 demonstrates good validity, reliability, and responsiveness and can be used to measure QOL for Chinese patients with head and neck cancer.

Original language	English (US)
Pages (from-to)	1555-1564
Number of pages	10
Journal	Supportive Care in Cancer
Volume	20
Issue number	7
DOIs	https://doi.org/10.1007/s00520-011-1247-0
State	Published - Jul 2012
Externally published	Yes

Keywords

FACT-H& N
Head and neck cancer
Psychometric properties
QLICP-HN
QLQ-H& N35
Quality of life
Standardized response mean

ASJC Scopus subject areas

Oncology

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10.1007/s00520-011-1247-0

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@article{84a83bb7c61c44b9b2f1c13dd2311d46,

title = "Development and validation of the simplified Chinese version of EORTC QLQ-H&N35 for patients with head and neck cancer",

abstract = "Goals A simplified Chinese version of EORTC QLQH& N35 was developed using strict translation procedures according to EORTC translation guidelines. Psychometric properties were evaluated. Patients and methods Three instruments (QLQ-H&N35, QLICP-HN, and FACT-H&N) were used in a sample of 133 patients with head and neck cancer at the time of their admission to the hospital. Each patient was assessed for the second time 1-2 days after hospitalization so that the test-retest reliability could be calculated. A sub-sample of patients was sampled and measured for the third time at discharge in order to evaluate the responsiveness. Results Correlation analysis among domains and items of the three instruments showed good construct validity and criterion-related validity. Comparisons of QLQ-H&N35 between treatment groups and age groups supported clinical validity. The internal consistency reliability measured by Cronbach's coefficient ? was greater than 0.70 for all multiitem domains, and test-retest reliability coefficients for all domains were greater than 0.80, ranging from 0.88 to 0.95. Score changes between pre- and post-treatment were observed in 6 out of 18 domains, with effect size SRM ranging from 0.27 to 0.87. Conclusions The simplified Chinese version of QLQH& N35 demonstrates good validity, reliability, and responsiveness and can be used to measure QOL for Chinese patients with head and neck cancer.",

keywords = "FACT-H& N, Head and neck cancer, Psychometric properties, QLICP-HN, QLQ-H& N35, Quality of life, Standardized response mean",

author = "Zheng Yang and Qiong Meng and Jiahong Luo and Qian Lu and Xiaojiang Li and Gaofeng Li and Chonghua Wan",

note = "Funding Information: Acknowledgements In carrying out this research project, we received substantial assistance from Karen West, Jane Blazeby, Neil Aaronson, and Mirjam Sprangers at EORTC and many staff, including Xueliang Tang and Yubo Lu at the Yunnan Tumor Hospital and Mallori Henceroth from the University of Houston. We sincerely appreciate their kind help. This work was supported by The Natural Sciences Funds of Yunnan Province (2008CD055) and Research Fund of Top Talent Project of Guangdong Medical College (XG1004).",

year = "2012",

month = jul,

doi = "10.1007/s00520-011-1247-0",

language = "English (US)",

volume = "20",

pages = "1555--1564",

journal = "Supportive Care in Cancer",

issn = "0941-4355",

publisher = "Springer Verlag",

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TY - JOUR

T1 - Development and validation of the simplified Chinese version of EORTC QLQ-H&N35 for patients with head and neck cancer

AU - Yang, Zheng

AU - Meng, Qiong

AU - Luo, Jiahong

AU - Lu, Qian

AU - Li, Xiaojiang

AU - Li, Gaofeng

AU - Wan, Chonghua

N1 - Funding Information: Acknowledgements In carrying out this research project, we received substantial assistance from Karen West, Jane Blazeby, Neil Aaronson, and Mirjam Sprangers at EORTC and many staff, including Xueliang Tang and Yubo Lu at the Yunnan Tumor Hospital and Mallori Henceroth from the University of Houston. We sincerely appreciate their kind help. This work was supported by The Natural Sciences Funds of Yunnan Province (2008CD055) and Research Fund of Top Talent Project of Guangdong Medical College (XG1004).

PY - 2012/7

Y1 - 2012/7

N2 - Goals A simplified Chinese version of EORTC QLQH& N35 was developed using strict translation procedures according to EORTC translation guidelines. Psychometric properties were evaluated. Patients and methods Three instruments (QLQ-H&N35, QLICP-HN, and FACT-H&N) were used in a sample of 133 patients with head and neck cancer at the time of their admission to the hospital. Each patient was assessed for the second time 1-2 days after hospitalization so that the test-retest reliability could be calculated. A sub-sample of patients was sampled and measured for the third time at discharge in order to evaluate the responsiveness. Results Correlation analysis among domains and items of the three instruments showed good construct validity and criterion-related validity. Comparisons of QLQ-H&N35 between treatment groups and age groups supported clinical validity. The internal consistency reliability measured by Cronbach's coefficient ? was greater than 0.70 for all multiitem domains, and test-retest reliability coefficients for all domains were greater than 0.80, ranging from 0.88 to 0.95. Score changes between pre- and post-treatment were observed in 6 out of 18 domains, with effect size SRM ranging from 0.27 to 0.87. Conclusions The simplified Chinese version of QLQH& N35 demonstrates good validity, reliability, and responsiveness and can be used to measure QOL for Chinese patients with head and neck cancer.

AB - Goals A simplified Chinese version of EORTC QLQH& N35 was developed using strict translation procedures according to EORTC translation guidelines. Psychometric properties were evaluated. Patients and methods Three instruments (QLQ-H&N35, QLICP-HN, and FACT-H&N) were used in a sample of 133 patients with head and neck cancer at the time of their admission to the hospital. Each patient was assessed for the second time 1-2 days after hospitalization so that the test-retest reliability could be calculated. A sub-sample of patients was sampled and measured for the third time at discharge in order to evaluate the responsiveness. Results Correlation analysis among domains and items of the three instruments showed good construct validity and criterion-related validity. Comparisons of QLQ-H&N35 between treatment groups and age groups supported clinical validity. The internal consistency reliability measured by Cronbach's coefficient ? was greater than 0.70 for all multiitem domains, and test-retest reliability coefficients for all domains were greater than 0.80, ranging from 0.88 to 0.95. Score changes between pre- and post-treatment were observed in 6 out of 18 domains, with effect size SRM ranging from 0.27 to 0.87. Conclusions The simplified Chinese version of QLQH& N35 demonstrates good validity, reliability, and responsiveness and can be used to measure QOL for Chinese patients with head and neck cancer.

KW - FACT-H& N

KW - Head and neck cancer

KW - Psychometric properties

KW - QLICP-HN

KW - QLQ-H& N35

KW - Quality of life

KW - Standardized response mean

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JO - Supportive Care in Cancer

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ER -

Development and validation of the simplified Chinese version of EORTC QLQ-H&N35 for patients with head and neck cancer

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Keywords

ASJC Scopus subject areas

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