TY - JOUR
T1 - Diabetes mellitus, smoking, and the risk for asymptomatic peripheral arterial disease
T2 - Whom should we screen?
AU - Eason, Sharon L.
AU - Petersen, Nancy J.
AU - Suarez-Almazor, Maria
AU - Davis, Barry
AU - Collins, Tracie C.
PY - 2005
Y1 - 2005
N2 - Objective: To describe coexisting medical conditions and lifestyle factors associated with asymptomatic peripheral arterial disease (PAD) in a population of white, African American, and Hispanic patients. Study Design and Setting: White, African American, and Hispanic patients 50 years or older were recruited for this cross-sectional study from 4 primary care clinics in Houston, TX. Patients with an ankle-brachial index (ABI) < 0.9 and without leg symptoms typical of PAD were diagnosed with asymptomatic PAD. Results: 403 patients were screened for PAD. Of these, 25 (6.2%) had asymptomatic PAD. Compared with patients without PAD, diabetes mellitus ([OR] 3.8; 95% CI 1.6, 9.0) and a history of smoking at least 1 pack of cigarettes per day ([OR] 2.5; 95% CI 1.1, 6.0) were significantly associated with asymptomatic PAD. An interaction effect existed between diabetes mellitus and smoking at least 1 pack of cigarettes per day. Diabetes mellitus combined with heavy smoking showed the highest predicted value positive (15%) and the highest specificity (92%). A lack of both demonstrated low rates for predicting asymptomatic PAD (predicted value positive, 1%). Conclusion: The ankle-brachial index could become routine screening among patients with diabetes mellitus and/or who smoke.
AB - Objective: To describe coexisting medical conditions and lifestyle factors associated with asymptomatic peripheral arterial disease (PAD) in a population of white, African American, and Hispanic patients. Study Design and Setting: White, African American, and Hispanic patients 50 years or older were recruited for this cross-sectional study from 4 primary care clinics in Houston, TX. Patients with an ankle-brachial index (ABI) < 0.9 and without leg symptoms typical of PAD were diagnosed with asymptomatic PAD. Results: 403 patients were screened for PAD. Of these, 25 (6.2%) had asymptomatic PAD. Compared with patients without PAD, diabetes mellitus ([OR] 3.8; 95% CI 1.6, 9.0) and a history of smoking at least 1 pack of cigarettes per day ([OR] 2.5; 95% CI 1.1, 6.0) were significantly associated with asymptomatic PAD. An interaction effect existed between diabetes mellitus and smoking at least 1 pack of cigarettes per day. Diabetes mellitus combined with heavy smoking showed the highest predicted value positive (15%) and the highest specificity (92%). A lack of both demonstrated low rates for predicting asymptomatic PAD (predicted value positive, 1%). Conclusion: The ankle-brachial index could become routine screening among patients with diabetes mellitus and/or who smoke.
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U2 - 10.3122/jabfm.18.5.355
DO - 10.3122/jabfm.18.5.355
M3 - Article
C2 - 16148245
AN - SCOPUS:27944465378
SN - 0893-8652
VL - 18
SP - 355
EP - 361
JO - Journal of the American Board of Family Practice
JF - Journal of the American Board of Family Practice
IS - 5
ER -