Abstract
The cytological, histological, and ultrastructural morphology of transcutaneous bone aspirates from five patients with eosinophilic granuloma of bone were studied. Use of this combined approach enabled us to make a definitive diagnosis of eosinophilic granuloma from a small quantity of tissue without having to resort to open biopsy. By light microscopy, eosinophilic granuloma is composed of a polymorphous infiltrate of characteristic lobulated histiocytes, eosinophils, polymorphonuclear leukocytes, and giant cells. Each specimen examined ultrastructurally demonstrated the characteristic Langerhans granule-containing histiocyte. Eosinophilic granuloma is a benign lesion which is readily diagnosed by this technique, and more aggressive diagnostic procedures usually are not warranted.
Original language | English (US) |
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Pages (from-to) | 1284-1290 |
Number of pages | 7 |
Journal | Unknown Journal |
Volume | 62 |
Issue number | 8 |
DOIs | |
State | Published - 1980 |
ASJC Scopus subject areas
- Surgery
- Orthopedics and Sports Medicine