Directed evolution to investigate steric control of enzymatic oxidosqualene cyclization. An isoleucine-to-valine mutation in cycloartenol synthase allows lanosterol and parkeol biosynthesis [9]

Elizabeth A. Hart, Ling Hua, Lisa B. Darr, William K. Wilson, Jihai Pang, Seiichi P.T. Matsuda

Research output: Contribution to journalLetterpeer-review

95 Scopus citations
Original languageEnglish (US)
Pages (from-to)9887-9888
Number of pages2
JournalJournal of the American Chemical Society
Volume121
Issue number42
DOIs
StatePublished - Oct 27 1999
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry
  • Biochemistry
  • Colloid and Surface Chemistry

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