Disease proteomics

Research output: Contribution to journalReview articlepeer-review

900 Scopus citations

Abstract

The sequencing of the human genome and that of numerous pathogens has opened the door for proteomics by providing a sequence-based framework for mining proteomes. As a result, there is intense interest in applying proteomics to foster a better understanding of disease processes, develop new biomarkers for diagnosis and early detection of disease, and accelerate drug development This interest creates numerous opportunities as well as challenges to meet the needs for high sensitivity and high throughput required for disease-related investigations.

Original languageEnglish (US)
Pages (from-to)226-232
Number of pages7
JournalNature
Volume422
Issue number6928
DOIs
StatePublished - Mar 13 2003
Externally publishedYes

ASJC Scopus subject areas

  • General

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