Dissociation between suppressive and facilitating effects of aversive stimuli on behavior by benzodiazepines. A review and reinterpretation

Robert Dantzer

doi:10.1016/0364-7722(78)90020-6

Dissociation between suppressive and facilitating effects of aversive stimuli on behavior by benzodiazepines. A review and reinterpretation

Robert Dantzer

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Abstract

1. 1. Evidence showing that benzodiazepine derivatives release behavior which has been suppressed by punishment or non-reinforcement but do not prevent facilitating effects of aversive events on behavior is reviewed. 2. 2. The behavioral changes observed after benzodiazepine treatment appear to be due to a response perseverance effect which can be traced back to a selective interference of the drug treatment with the mechanisms controlling the processing of response-associated cues.

Original language	English (US)
Pages (from-to)	33-40
Number of pages	8
Journal	Progress in Neuro-Psychopharmacology
Volume	2
Issue number	1
DOIs	https://doi.org/10.1016/0364-7722(78)90020-6
State	Published - 1978
Externally published	Yes

Keywords

avoidance
behavior
behavioral facilitation
behavioral suppression
benzodiazepines
non-reinforcement
punishment
response perseverance

ASJC Scopus subject areas

General Neuroscience
Pharmacology, Toxicology and Pharmaceutics(all)
Psychiatry and Mental health
Pharmacology (medical)

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10.1016/0364-7722(78)90020-6

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title = "Dissociation between suppressive and facilitating effects of aversive stimuli on behavior by benzodiazepines. A review and reinterpretation",

abstract = "1. 1. Evidence showing that benzodiazepine derivatives release behavior which has been suppressed by punishment or non-reinforcement but do not prevent facilitating effects of aversive events on behavior is reviewed. 2. 2. The behavioral changes observed after benzodiazepine treatment appear to be due to a response perseverance effect which can be traced back to a selective interference of the drug treatment with the mechanisms controlling the processing of response-associated cues.",

keywords = "avoidance, behavior, behavioral facilitation, behavioral suppression, benzodiazepines, non-reinforcement, punishment, response perseverance",

author = "Robert Dantzer",

note = "Funding Information: Many of the ideas developed in this review comments and suggestions made by Dr. Bignami acknowledges the financial support received Recherche Agronomigue Recherches Veterinaires, National de la Sante de la Recherche Medicale",

year = "1978",

doi = "10.1016/0364-7722(78)90020-6",

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PY - 1978

Y1 - 1978

N2 - 1. 1. Evidence showing that benzodiazepine derivatives release behavior which has been suppressed by punishment or non-reinforcement but do not prevent facilitating effects of aversive events on behavior is reviewed. 2. 2. The behavioral changes observed after benzodiazepine treatment appear to be due to a response perseverance effect which can be traced back to a selective interference of the drug treatment with the mechanisms controlling the processing of response-associated cues.

AB - 1. 1. Evidence showing that benzodiazepine derivatives release behavior which has been suppressed by punishment or non-reinforcement but do not prevent facilitating effects of aversive events on behavior is reviewed. 2. 2. The behavioral changes observed after benzodiazepine treatment appear to be due to a response perseverance effect which can be traced back to a selective interference of the drug treatment with the mechanisms controlling the processing of response-associated cues.

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KW - behavior

KW - behavioral facilitation

KW - behavioral suppression

KW - benzodiazepines

KW - non-reinforcement

KW - punishment

KW - response perseverance

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JO - Progress in Neuro-Psychopharmacology

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Dissociation between suppressive and facilitating effects of aversive stimuli on behavior by benzodiazepines. A review and reinterpretation

Abstract

Keywords

ASJC Scopus subject areas

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