DNA-dependent protein kinase and ataxia telangiectasia mutated (ATM) promote cell survival in response to NK314, a topoisomerase IIα inhibitor

Medicine & Life Sciences

• NK314 100%
• DNA-Activated Protein Kinase 62%
• Topoisomerase II Inhibitors 60%
• Ataxia Telangiectasia 54%
• Cell Survival 32%
• Type II DNA Topoisomerase 13%
• 2-(4-morpholinyl)-4H-1-benzopyran-4-one 12%
• Double-Stranded DNA Breaks 12%
• benzo(c)phenanthridine 10%
• 8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one 10%
• 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one 9%
• DNA 8%
• Pyrans 8%
• Recombinational DNA Repair 6%
• Pulsed Field Gel Electrophoresis 6%
• Alkaloids 5%
• Chlorides 5%
• Protein Kinase Inhibitors 5%
• DNA Repair 4%
• Catalytic Domain 4%
• Phosphorylation 3%