DNA distribution patterns in early gastric carcinomas. A feulgen cytometric study of gastric brush smears

Bogdan Czerniak; Fritz Herz; Leopold G. Koss

doi:10.1002/1097-0142(19870101)59:1<113::AID-CNCR2820590124>3.0.CO;2-1

DNA distribution patterns in early gastric carcinomas. A feulgen cytometric study of gastric brush smears

Bogdan Czerniak, Fritz Herz, Leopold G. Koss

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

DNA distribution patterns were studied by cytophotometry in 20 Feulgen‐stained brush smears of early gastric carcinomas. Two different DNA distribution patterns, classified as predominantly diploid and aneuploid, were correlated with histologic data. Six of seven carcinomas of diffuse type were predominantly diploid. By contrast, 11 of 13 intestinal type carcinomas were aneuploid and two were diploid. Since the DNA distribution patterns recorded in this study were previously observed in advanced gastric carcinomas, this would suggest that the basic genetic make‐up of the tumors does not change with tumor progression. Cancer 59:113–117, 1987.

Original language	English (US)
Pages (from-to)	113-117
Number of pages	5
Journal	Cancer
Volume	59
Issue number	1
DOIs	https://doi.org/10.1002/1097-0142(19870101)59:1<113::AID-CNCR2820590124>3.0.CO;2-1
State	Published - Jan 1 1987
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cancer Research

Access to Document

10.1002/1097-0142(19870101)59:1<113::AID-CNCR2820590124>3.0.CO;2-1

Cite this

@article{7296efbdf8384ac0981c40a4421374eb,

title = "DNA distribution patterns in early gastric carcinomas. A feulgen cytometric study of gastric brush smears",

abstract = "DNA distribution patterns were studied by cytophotometry in 20 Feulgen‐stained brush smears of early gastric carcinomas. Two different DNA distribution patterns, classified as predominantly diploid and aneuploid, were correlated with histologic data. Six of seven carcinomas of diffuse type were predominantly diploid. By contrast, 11 of 13 intestinal type carcinomas were aneuploid and two were diploid. Since the DNA distribution patterns recorded in this study were previously observed in advanced gastric carcinomas, this would suggest that the basic genetic make‐up of the tumors does not change with tumor progression. Cancer 59:113–117, 1987.",

author = "Bogdan Czerniak and Fritz Herz and Koss, {Leopold G.}",

year = "1987",

month = jan,

day = "1",

doi = "10.1002/1097-0142(19870101)59:1<113::AID-CNCR2820590124>3.0.CO;2-1",

language = "English (US)",

volume = "59",

pages = "113--117",

journal = "Cancer",

issn = "0008-543X",

publisher = "John Wiley and Sons Inc.",

number = "1",

}

TY - JOUR

T1 - DNA distribution patterns in early gastric carcinomas. A feulgen cytometric study of gastric brush smears

AU - Czerniak, Bogdan

AU - Herz, Fritz

AU - Koss, Leopold G.

PY - 1987/1/1

Y1 - 1987/1/1

N2 - DNA distribution patterns were studied by cytophotometry in 20 Feulgen‐stained brush smears of early gastric carcinomas. Two different DNA distribution patterns, classified as predominantly diploid and aneuploid, were correlated with histologic data. Six of seven carcinomas of diffuse type were predominantly diploid. By contrast, 11 of 13 intestinal type carcinomas were aneuploid and two were diploid. Since the DNA distribution patterns recorded in this study were previously observed in advanced gastric carcinomas, this would suggest that the basic genetic make‐up of the tumors does not change with tumor progression. Cancer 59:113–117, 1987.

AB - DNA distribution patterns were studied by cytophotometry in 20 Feulgen‐stained brush smears of early gastric carcinomas. Two different DNA distribution patterns, classified as predominantly diploid and aneuploid, were correlated with histologic data. Six of seven carcinomas of diffuse type were predominantly diploid. By contrast, 11 of 13 intestinal type carcinomas were aneuploid and two were diploid. Since the DNA distribution patterns recorded in this study were previously observed in advanced gastric carcinomas, this would suggest that the basic genetic make‐up of the tumors does not change with tumor progression. Cancer 59:113–117, 1987.

UR - http://www.scopus.com/inward/record.url?scp=0023089277&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023089277&partnerID=8YFLogxK

U2 - 10.1002/1097-0142(19870101)59:1<113::AID-CNCR2820590124>3.0.CO;2-1

DO - 10.1002/1097-0142(19870101)59:1<113::AID-CNCR2820590124>3.0.CO;2-1

M3 - Article

C2 - 2431753

AN - SCOPUS:0023089277

SN - 0008-543X

VL - 59

SP - 113

EP - 117

JO - Cancer

JF - Cancer

IS - 1

ER -

DNA distribution patterns in early gastric carcinomas. A feulgen cytometric study of gastric brush smears

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this