Abstract
The diagnosis of Parkinson disease (PD) and dementia with Lewy bodies (DLB) is often not straightforward. When PD symptoms are atypical or overlap with other diseases (eg, essential tremor [ET] or drug induced), [123I] N-ω-fluoropropyl-2β-carbomethoxy-3b-(4-iodophenyl) nortropane ([ 123I]FP-CIT) single-photon emission computed tomography (SPECT) can improve the diagnostic accuracy. The potential side effects of medications for PD may be avoided, if [123I]FP-CIT SPECT is normal. [ 123I]FP-CIT SPECT is helpful in the diagnosis of DLB, differentiating it from other causes of dementia such as Alzheimer disease (AD).
Original language | English (US) |
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Pages (from-to) | 459-467 |
Number of pages | 9 |
Journal | PET Clinics |
Volume | 8 |
Issue number | 4 |
DOIs | |
State | Published - Oct 2013 |
Externally published | Yes |
Keywords
- Dementia
- Dopamine
- Parkinson disease
- SPECT
ASJC Scopus subject areas
- Radiation
- Radiology Nuclear Medicine and imaging