Doxorubin, mitomycin, and 5-FU (DMF) in the treatment of hormone-resistant stage D prostate cancer: A preliminary report

C. J. Logothetis, A. C. Von Eschenbach, M. L. Samuels

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Fifteen patients with advanced stage D hormone-resistant prostate cancer were treated with the combination of doxorubin, mitomycin, and 5-FU. Nine patients (60%) had objective responses, with a mean duration of 27.9 weeks. No responding patient has relapsed. Although three patients developed a culture-negative leukopenic fever, no deaths from chemotherapy occurred. Preliminary results with doxorubin, mitomycin, and 5-FU indicate that this is a very effective chemotherapy regimen, resulting in a high objective response rate in metastatic prostate cancer.

Original languageEnglish (US)
Pages (from-to)57-63
Number of pages7
JournalCancer Treatment Reports
Volume66
Issue number1
StatePublished - 1982

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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