TY - JOUR
T1 - Effect of age and race on quality of life in young breast cancer survivors
AU - Morrow, Phuong Khanh
AU - Broxson, Anita C.
AU - Munsell, Mark F.
AU - Basen-Enquist, Karen
AU - Rosenblum, Carol K.
AU - Schover, Leslie R.
AU - Nguyen, Lynne H.
AU - Hsu, Limin
AU - Castillo, Lilibeth
AU - Hahn, Karin M.
AU - Litton, Jennifer K.
AU - Kwiatkowski, Danielle N.
AU - Hortobagyi, Gabriel N.
N1 - Funding Information:
This study received support from the Patient-Reported Outcomes, Survey, and Population Research (PROSPR) Shared Resource (National Cancer Institute at the National Institutes of Health [No. CA 16672]) and the Young Breast Cancer Survivors' Program at the University of Texas MD Anderson Cancer Center.
PY - 2014/4
Y1 - 2014/4
N2 - Background Given their early age at diagnosis, young breast cancer survivors (YBCSs) face issues that differ widely from their older counterparts. Patients and Methods We mailed a survey to 2209 patients who were ≤ 45 years at the time of breast cancer (BC) diagnosis. Each survey was composed of the Quality of Life in Adult Cancer Survivors instrument, Menopause Symptom Scale, and questions aimed at obtaining pertinent background information. Results One thousand ninety patients completed the survey. Mean age at time of diagnosis was 39.5 years; median years from diagnosis was 6.6 years. Distress related to vaginal dryness (P =.0002) and pain from intercourse (P =.0014) was significantly higher in patients who were < 5 years from diagnosis compared with those > 10 years from diagnosis. In the area of financial problems, black women had greater distress than did white women (P =.0010). Compared with white women, Hispanic women had worse family distress scores (P =.0028) and summary cancer-specific scores (P =.0076). Patients > 10 years from diagnosis had less sexual interest (P =.003) than did women who were closer to diagnosis. Women ≥ 40 years at diagnosis had significantly lower sexual interest (P =.0016) than did women < 40 years. Stage and neoadjuvant chemotherapy did not have a significant effect on quality of life (QOL). Conclusion Even in comparison to stage and neoadjuvant chemotherapy, race, age at diagnosis, and time from diagnosis have significant long-term effects on QOL after treatment for BC.
AB - Background Given their early age at diagnosis, young breast cancer survivors (YBCSs) face issues that differ widely from their older counterparts. Patients and Methods We mailed a survey to 2209 patients who were ≤ 45 years at the time of breast cancer (BC) diagnosis. Each survey was composed of the Quality of Life in Adult Cancer Survivors instrument, Menopause Symptom Scale, and questions aimed at obtaining pertinent background information. Results One thousand ninety patients completed the survey. Mean age at time of diagnosis was 39.5 years; median years from diagnosis was 6.6 years. Distress related to vaginal dryness (P =.0002) and pain from intercourse (P =.0014) was significantly higher in patients who were < 5 years from diagnosis compared with those > 10 years from diagnosis. In the area of financial problems, black women had greater distress than did white women (P =.0010). Compared with white women, Hispanic women had worse family distress scores (P =.0028) and summary cancer-specific scores (P =.0076). Patients > 10 years from diagnosis had less sexual interest (P =.003) than did women who were closer to diagnosis. Women ≥ 40 years at diagnosis had significantly lower sexual interest (P =.0016) than did women < 40 years. Stage and neoadjuvant chemotherapy did not have a significant effect on quality of life (QOL). Conclusion Even in comparison to stage and neoadjuvant chemotherapy, race, age at diagnosis, and time from diagnosis have significant long-term effects on QOL after treatment for BC.
KW - Age at diagnosis
KW - Survey
KW - Years from diagnosis
UR - http://www.scopus.com/inward/record.url?scp=84896396201&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84896396201&partnerID=8YFLogxK
U2 - 10.1016/j.clbc.2013.10.003
DO - 10.1016/j.clbc.2013.10.003
M3 - Article
C2 - 24461458
AN - SCOPUS:84896396201
SN - 1526-8209
VL - 14
SP - e21-e31
JO - Clinical breast cancer
JF - Clinical breast cancer
IS - 2
ER -