Effectiveness of low-dose radiation for primary cutaneous anaplastic large cell lymphoma

Grace L. Smith; Madeleine Duvic; Zeinab Abou Yehia; Pamela Allen; Naveen Garg; Tina Suki; Sarah A. Milgrom; Chelsea C. Pinnix; Yasuhiro Oki; Joseph D. Khoury; Bouthaina S. Dabaja

doi:10.1016/j.adro.2017.06.004

Effectiveness of low-dose radiation for primary cutaneous anaplastic large cell lymphoma

Grace L. Smith, Madeleine Duvic, Zeinab Abou Yehia, Pamela Allen, Naveen Garg, Tina Suki, Sarah A. Milgrom, Chelsea C. Pinnix, Yasuhiro Oki, Joseph D. Khoury, Bouthaina S. Dabaja

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6 Scopus citations

Abstract

Primary cutaneous anaplastic large cell lymphoma (pcALCL) is conventionally treated with radiation therapy (RT) doses ≥30 Gy. In a series of 21 patients with pcALCL, responses were examined after a range of RT doses: ≤20 Gy, 20 to 29 Gy, and ≥30 Gy. Three-year freedom from local relapse was 100%, 86%, and 100%, respectively (P = .28). Low-dose RT appeared to be an acceptable approach for local control in the setting of the indolent, chronic course of pcALCL in this series.

Original language	English (US)
Pages (from-to)	363-369
Number of pages	7
Journal	Advances in Radiation Oncology
Volume	2
Issue number	3
DOIs	https://doi.org/10.1016/j.adro.2017.06.004
State	Published - Jul 2017

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging

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title = "Effectiveness of low-dose radiation for primary cutaneous anaplastic large cell lymphoma",

abstract = "Primary cutaneous anaplastic large cell lymphoma (pcALCL) is conventionally treated with radiation therapy (RT) doses ≥30 Gy. In a series of 21 patients with pcALCL, responses were examined after a range of RT doses: ≤20 Gy, 20 to 29 Gy, and ≥30 Gy. Three-year freedom from local relapse was 100%, 86%, and 100%, respectively (P = .28). Low-dose RT appeared to be an acceptable approach for local control in the setting of the indolent, chronic course of pcALCL in this series.",

author = "Smith, {Grace L.} and Madeleine Duvic and Yehia, {Zeinab Abou} and Pamela Allen and Naveen Garg and Tina Suki and Milgrom, {Sarah A.} and Pinnix, {Chelsea C.} and Yasuhiro Oki and Khoury, {Joseph D.} and Dabaja, {Bouthaina S.}",

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T1 - Effectiveness of low-dose radiation for primary cutaneous anaplastic large cell lymphoma

AU - Smith, Grace L.

AU - Duvic, Madeleine

AU - Yehia, Zeinab Abou

AU - Allen, Pamela

AU - Garg, Naveen

AU - Suki, Tina

AU - Milgrom, Sarah A.

AU - Pinnix, Chelsea C.

AU - Oki, Yasuhiro

AU - Khoury, Joseph D.

AU - Dabaja, Bouthaina S.

PY - 2017/7

Y1 - 2017/7

N2 - Primary cutaneous anaplastic large cell lymphoma (pcALCL) is conventionally treated with radiation therapy (RT) doses ≥30 Gy. In a series of 21 patients with pcALCL, responses were examined after a range of RT doses: ≤20 Gy, 20 to 29 Gy, and ≥30 Gy. Three-year freedom from local relapse was 100%, 86%, and 100%, respectively (P = .28). Low-dose RT appeared to be an acceptable approach for local control in the setting of the indolent, chronic course of pcALCL in this series.

AB - Primary cutaneous anaplastic large cell lymphoma (pcALCL) is conventionally treated with radiation therapy (RT) doses ≥30 Gy. In a series of 21 patients with pcALCL, responses were examined after a range of RT doses: ≤20 Gy, 20 to 29 Gy, and ≥30 Gy. Three-year freedom from local relapse was 100%, 86%, and 100%, respectively (P = .28). Low-dose RT appeared to be an acceptable approach for local control in the setting of the indolent, chronic course of pcALCL in this series.

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Effectiveness of low-dose radiation for primary cutaneous anaplastic large cell lymphoma

Abstract

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