TY - JOUR
T1 - Effects of estrogen on thermoregulatory tail vasomotion and heat-escape behavior in freely moving female rats
AU - Hosono, Takayoshi
AU - Chen, Xiao Ming
AU - Miyatsuji, Aya
AU - Yoda, Tamae
AU - Yoshida, Kyoko
AU - Yanase-Fujiwara, Motoko
AU - Kanosue, Kazuyuki
PY - 2001/5
Y1 - 2001/5
N2 - Effects of estrogen on thermoregulatory tail vasomotion and neat-escape behavior in freely moving female rats. Am J Physiol Regulatory Integrative Comp Physiol 280: R1341-R1347, 2001.- Effects of estrogen on thermoregulatory vasomotion and heat-escape behavior were investigated in ovariectomized female rats supplemented with estrogen (replaced estrogen rats) or control saline (low estrogen rats). First, we measured tail temperature of freely moving rats at ambient temperatures (Ta) between 13 and 31°C. Tail temperature of the low estrogen rats was higher than that of the replaced estrogen rats at Ta between 19 and 25°C, indicating that the low estrogen rats exhibit more skin vasodilation than the replaced estrogen rats. There was no significant difference in oxygen consumption and core temperature between the two groups. Second, we analyzed heat-escape behaviors in a hot chamber where rats could obtain cold air by moving in and out of a reward area. The low estrogen rats kept Ta at a lower level than did the replaced estrogen rats. These results imply that the lack of estrogen facilitates heat dissipation both by skin vasodilation and by heat-escape behavior. Ovariectomized rats may mimic climacteric hot flushes not only for autonomic skin vasomotor activity but also for thermoregulatory behavior.
AB - Effects of estrogen on thermoregulatory tail vasomotion and neat-escape behavior in freely moving female rats. Am J Physiol Regulatory Integrative Comp Physiol 280: R1341-R1347, 2001.- Effects of estrogen on thermoregulatory vasomotion and heat-escape behavior were investigated in ovariectomized female rats supplemented with estrogen (replaced estrogen rats) or control saline (low estrogen rats). First, we measured tail temperature of freely moving rats at ambient temperatures (Ta) between 13 and 31°C. Tail temperature of the low estrogen rats was higher than that of the replaced estrogen rats at Ta between 19 and 25°C, indicating that the low estrogen rats exhibit more skin vasodilation than the replaced estrogen rats. There was no significant difference in oxygen consumption and core temperature between the two groups. Second, we analyzed heat-escape behaviors in a hot chamber where rats could obtain cold air by moving in and out of a reward area. The low estrogen rats kept Ta at a lower level than did the replaced estrogen rats. These results imply that the lack of estrogen facilitates heat dissipation both by skin vasodilation and by heat-escape behavior. Ovariectomized rats may mimic climacteric hot flushes not only for autonomic skin vasomotor activity but also for thermoregulatory behavior.
KW - Autonomic thermoregulation
KW - Behavioral thermoregulation
KW - Hot flush
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U2 - 10.1152/ajpregu.2001.280.5.r1341
DO - 10.1152/ajpregu.2001.280.5.r1341
M3 - Article
C2 - 11294752
AN - SCOPUS:0035033977
SN - 0363-6119
VL - 280
SP - R1341-R1347
JO - American Journal of Physiology - Regulatory Integrative and Comparative Physiology
JF - American Journal of Physiology - Regulatory Integrative and Comparative Physiology
IS - 5 49-5
ER -