Effects of post-trial injection of β-endorphin on shock-induced fighting are dependent on baseline of fighting

A. Tazi, R. Dantzer, P. Mormede, M. Le Moal

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The effects of repeated post-trial administration of 10 μg/kg β-endorphin on the development of mutual fighting in pairs of rats submitted to various intensities of electric shock were investigated. β-Endorphin blocked the development of fighting responses when a low footshock intensity was used, but facilitated it when a high shock intensity was delivered. A detailed analysis of the relationship between shock intensity, baseline of fighting, and effects of β-endorphin showed that the effects of β-endorphin were dependent on the behavioral baseline rather than on shock intensity per se.

Original languageEnglish (US)
Pages (from-to)322-326
Number of pages5
JournalBehavioral and Neural Biology
Volume43
Issue number3
DOIs
StatePublished - May 1985
Externally publishedYes

ASJC Scopus subject areas

  • Physiology

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