Elastographic imaging of thermal lesions in soft tissue: A preliminary study in vitro

R. Jason Stafford; Faouzi Kallel; Roger E. Price; Douglas M. Cromeens; Thomas A. Krouskop; John D. Hazle; Jonathan Ophir

doi:10.1016/S0301-5629(98)00099-4

Elastographic imaging of thermal lesions in soft tissue: A preliminary study in vitro

R. Jason Stafford, Faouzi Kallel, Roger E. Price, Douglas M. Cromeens, Thomas A. Krouskop, John D. Hazle, Jonathan Ophir

Imaging Physics

Research output: Contribution to journal › Article › peer-review

64 Scopus citations

Abstract

The use of elastography for the visualization of thermal lesions in biological soft tissue in vitro was investigated. Thermal lesions were created in samples of postmortem ovine kidney using a surgical neodymium:YAG (Nd:YAG) laser. The kidney samples were cast in gel, and elastographic images of the lesions were constructed using sonographic information and external markers to locate the region of interest. Gross pathology of the kidney samples confirmed the dimensions of the lesions. Good correlation between the lesion length along the laser fiber axis and maximum diameter measured off of the fiber axis determined from elastographic images and gross pathology photographs was found.

Original language	English (US)
Pages (from-to)	1449-1458
Number of pages	10
Journal	Ultrasound in Medicine and Biology
Volume	24
Issue number	9
DOIs	https://doi.org/10.1016/S0301-5629(98)00099-4
State	Published - Dec 1998

Keywords

Elastography
High-intensity focused ultrasound
Magnetic resonance imaging
Minimally invasive surgery
Neodymium-YAG laser
Strain
Tissue ablation
Ultrasound

ASJC Scopus subject areas

Biophysics
Radiological and Ultrasound Technology
Acoustics and Ultrasonics

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10.1016/S0301-5629(98)00099-4

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@article{2e6dd37e47f147fba725c93ad5f14ee3,

title = "Elastographic imaging of thermal lesions in soft tissue: A preliminary study in vitro",

abstract = "The use of elastography for the visualization of thermal lesions in biological soft tissue in vitro was investigated. Thermal lesions were created in samples of postmortem ovine kidney using a surgical neodymium:YAG (Nd:YAG) laser. The kidney samples were cast in gel, and elastographic images of the lesions were constructed using sonographic information and external markers to locate the region of interest. Gross pathology of the kidney samples confirmed the dimensions of the lesions. Good correlation between the lesion length along the laser fiber axis and maximum diameter measured off of the fiber axis determined from elastographic images and gross pathology photographs was found.",

keywords = "Elastography, High-intensity focused ultrasound, Magnetic resonance imaging, Minimally invasive surgery, Neodymium-YAG laser, Strain, Tissue ablation, Ultrasound",

author = "Stafford, {R. Jason} and Faouzi Kallel and Price, {Roger E.} and Cromeens, {Douglas M.} and Krouskop, {Thomas A.} and Hazle, {John D.} and Jonathan Ophir",

note = "Funding Information: Supported in part by National Cancer Institute grant ROI-CA60520 and Program Project POI-CA64597 to the University of Texas Medical School.",

year = "1998",

month = dec,

doi = "10.1016/S0301-5629(98)00099-4",

language = "English (US)",

volume = "24",

pages = "1449--1458",

journal = "Ultrasound in Medicine and Biology",

issn = "0301-5629",

publisher = "Elsevier USA",

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T1 - Elastographic imaging of thermal lesions in soft tissue

T2 - A preliminary study in vitro

AU - Stafford, R. Jason

AU - Kallel, Faouzi

AU - Price, Roger E.

AU - Cromeens, Douglas M.

AU - Krouskop, Thomas A.

AU - Hazle, John D.

AU - Ophir, Jonathan

N1 - Funding Information: Supported in part by National Cancer Institute grant ROI-CA60520 and Program Project POI-CA64597 to the University of Texas Medical School.

PY - 1998/12

Y1 - 1998/12

N2 - The use of elastography for the visualization of thermal lesions in biological soft tissue in vitro was investigated. Thermal lesions were created in samples of postmortem ovine kidney using a surgical neodymium:YAG (Nd:YAG) laser. The kidney samples were cast in gel, and elastographic images of the lesions were constructed using sonographic information and external markers to locate the region of interest. Gross pathology of the kidney samples confirmed the dimensions of the lesions. Good correlation between the lesion length along the laser fiber axis and maximum diameter measured off of the fiber axis determined from elastographic images and gross pathology photographs was found.

AB - The use of elastography for the visualization of thermal lesions in biological soft tissue in vitro was investigated. Thermal lesions were created in samples of postmortem ovine kidney using a surgical neodymium:YAG (Nd:YAG) laser. The kidney samples were cast in gel, and elastographic images of the lesions were constructed using sonographic information and external markers to locate the region of interest. Gross pathology of the kidney samples confirmed the dimensions of the lesions. Good correlation between the lesion length along the laser fiber axis and maximum diameter measured off of the fiber axis determined from elastographic images and gross pathology photographs was found.

KW - Elastography

KW - High-intensity focused ultrasound

KW - Magnetic resonance imaging

KW - Minimally invasive surgery

KW - Neodymium-YAG laser

KW - Strain

KW - Tissue ablation

KW - Ultrasound

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DO - 10.1016/S0301-5629(98)00099-4

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AN - SCOPUS:0032411139

SN - 0301-5629

VL - 24

SP - 1449

EP - 1458

JO - Ultrasound in Medicine and Biology

JF - Ultrasound in Medicine and Biology

IS - 9

ER -

Elastographic imaging of thermal lesions in soft tissue: A preliminary study in vitro

Abstract

Keywords

ASJC Scopus subject areas

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