Emerging Concepts in Managing Malignancy in Kidney Transplant Patients

Brittany Schreiber; Maen Abdelrahim; Ala Abudayyeh; Naoka Murakami

doi:10.1016/j.semnephrol.2022.01.003

Emerging Concepts in Managing Malignancy in Kidney Transplant Patients

Brittany Schreiber, Maen Abdelrahim, Ala Abudayyeh, Naoka Murakami

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Abstract

Cancer remains a significant cause of morbidity and mortality in kidney transplant recipients, due to long-term immunosuppression. Salient issues to consider in decreasing the burden of malignancy among kidney transplant recipients include pretransplant recipient evaluation, post-transplant screening and monitoring, and optimal treatment strategies for the kidney transplant recipients with cancer. In this review, we address cancer incidence and outcomes, approaches to cancer screening and monitoring pretransplant and post-transplant, as well as treatment strategies, immunosuppressive management, and multidisciplinary approaches in the kidney transplant recipients with cancer.

Original language	English (US)
Pages (from-to)	63-75
Number of pages	13
Journal	Seminars in Nephrology
Volume	42
Issue number	1
DOIs	https://doi.org/10.1016/j.semnephrol.2022.01.003
State	Published - Jan 2022

Keywords

Kidney transplant
PTLD
cancer
immunotherapy
oncology
wait time

ASJC Scopus subject areas

Nephrology

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10.1016/j.semnephrol.2022.01.003

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title = "Emerging Concepts in Managing Malignancy in Kidney Transplant Patients",

abstract = "Cancer remains a significant cause of morbidity and mortality in kidney transplant recipients, due to long-term immunosuppression. Salient issues to consider in decreasing the burden of malignancy among kidney transplant recipients include pretransplant recipient evaluation, post-transplant screening and monitoring, and optimal treatment strategies for the kidney transplant recipients with cancer. In this review, we address cancer incidence and outcomes, approaches to cancer screening and monitoring pretransplant and post-transplant, as well as treatment strategies, immunosuppressive management, and multidisciplinary approaches in the kidney transplant recipients with cancer.",

keywords = "Kidney transplant, PTLD, cancer, immunotherapy, oncology, wait time",

author = "Brittany Schreiber and Maen Abdelrahim and Ala Abudayyeh and Naoka Murakami",

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AU - Schreiber, Brittany

AU - Abdelrahim, Maen

AU - Abudayyeh, Ala

AU - Murakami, Naoka

PY - 2022/1

Y1 - 2022/1

N2 - Cancer remains a significant cause of morbidity and mortality in kidney transplant recipients, due to long-term immunosuppression. Salient issues to consider in decreasing the burden of malignancy among kidney transplant recipients include pretransplant recipient evaluation, post-transplant screening and monitoring, and optimal treatment strategies for the kidney transplant recipients with cancer. In this review, we address cancer incidence and outcomes, approaches to cancer screening and monitoring pretransplant and post-transplant, as well as treatment strategies, immunosuppressive management, and multidisciplinary approaches in the kidney transplant recipients with cancer.

AB - Cancer remains a significant cause of morbidity and mortality in kidney transplant recipients, due to long-term immunosuppression. Salient issues to consider in decreasing the burden of malignancy among kidney transplant recipients include pretransplant recipient evaluation, post-transplant screening and monitoring, and optimal treatment strategies for the kidney transplant recipients with cancer. In this review, we address cancer incidence and outcomes, approaches to cancer screening and monitoring pretransplant and post-transplant, as well as treatment strategies, immunosuppressive management, and multidisciplinary approaches in the kidney transplant recipients with cancer.

KW - Kidney transplant

KW - PTLD

KW - cancer

KW - immunotherapy

KW - oncology

KW - wait time

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Emerging Concepts in Managing Malignancy in Kidney Transplant Patients

Abstract

Keywords

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