TY - JOUR
T1 - Emerging endoscopic techniques for the identification of esophageal disease
AU - Triadafilopoulos, George
AU - Akiyama, Junichi
N1 - Publisher Copyright:
© 2016 Informa UK Limited.
PY - 2016/5/3
Y1 - 2016/5/3
N2 - Esophageal diseases, both benign and malignant, impose an increasing burden to global health. In the West, gastroesophageal reflux disease (GERD) and Barretts esophagus are increasing in prevalence and impact. In the East, squamous esophageal cancer remains a large burden, but increasingly, precancerous lesions related to GERD are recognized. We review the various advanced endoscopic techniques that have been developed to improve the accuracy of endoscopic identification of esophageal disease. These techniques are designed to increase the sensitivity of detecting disease and high-risk lesions, enable targeted biopsies, decrease total number of biopsies and costs for surveillance, but also guide therapy in real-time. After proper clinical validation, the widespread use of these technologies will lead to improved outcomes, mostly in cancer prevention.
AB - Esophageal diseases, both benign and malignant, impose an increasing burden to global health. In the West, gastroesophageal reflux disease (GERD) and Barretts esophagus are increasing in prevalence and impact. In the East, squamous esophageal cancer remains a large burden, but increasingly, precancerous lesions related to GERD are recognized. We review the various advanced endoscopic techniques that have been developed to improve the accuracy of endoscopic identification of esophageal disease. These techniques are designed to increase the sensitivity of detecting disease and high-risk lesions, enable targeted biopsies, decrease total number of biopsies and costs for surveillance, but also guide therapy in real-time. After proper clinical validation, the widespread use of these technologies will lead to improved outcomes, mostly in cancer prevention.
KW - Advanced imaging
KW - Barrett's esophagus
KW - Esophageal cancer
KW - Esophageal dysplasia
KW - Esophagus
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U2 - 10.1586/17474124.2016.1140037
DO - 10.1586/17474124.2016.1140037
M3 - Review article
C2 - 26753504
AN - SCOPUS:84958528451
SN - 1747-4124
VL - 10
SP - 605
EP - 613
JO - Expert Review of Gastroenterology and Hepatology
JF - Expert Review of Gastroenterology and Hepatology
IS - 5
ER -