Emerging prevention and treatment strategies to control COVID-19

Vipul K. Singh; Abhishek Mishra; Shubhra Singh; Premranjan Kumar; Manisha Singh; Chinnaswamy Jagannath; Arshad Khan

doi:10.3390/pathogens9060501

Emerging prevention and treatment strategies to control COVID-19

Vipul K. Singh, Abhishek Mishra, Shubhra Singh, Premranjan Kumar, Manisha Singh, Chinnaswamy Jagannath, Arshad Khan

Lymphoma-Myeloma

Research output: Contribution to journal › Review article › peer-review

18 Scopus citations

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has now become a serious global threat after inflicting more than 8 million infections and 425,000 deaths in less than 6 months. Currently, no definitive treatment or prevention therapy exists for COVID-19. The unprecedented rise of this pandemic has rapidly fueled research efforts to discover and develop new vaccines and treatment strategies against this novel coronavirus. While hundreds of vaccines/therapeutics are still in the preclinical or early stage of clinical development, a few of them have shown promising results in controlling the infection. Here, in this review, we discuss the promising vaccines and treatment options for COVID-19, their challenges, and potential alternative strategies.

Original language	English (US)
Article number	501
Pages (from-to)	1-16
Number of pages	16
Journal	Pathogens
Volume	9
Issue number	6
DOIs	https://doi.org/10.3390/pathogens9060501
State	Published - Jun 2020

Keywords

COVID-19
Convalescent plasma
Drug repurposing
SARS-CoV-2
Stem cell therapy
Vaccine interventions

ASJC Scopus subject areas

Immunology and Allergy
Molecular Biology
General Immunology and Microbiology
Microbiology (medical)
Infectious Diseases

Access to Document

10.3390/pathogens9060501

Cite this

@article{5d2fd693ab8a47b4a676351f8c693f0c,

title = "Emerging prevention and treatment strategies to control COVID-19",

abstract = "Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has now become a serious global threat after inflicting more than 8 million infections and 425,000 deaths in less than 6 months. Currently, no definitive treatment or prevention therapy exists for COVID-19. The unprecedented rise of this pandemic has rapidly fueled research efforts to discover and develop new vaccines and treatment strategies against this novel coronavirus. While hundreds of vaccines/therapeutics are still in the preclinical or early stage of clinical development, a few of them have shown promising results in controlling the infection. Here, in this review, we discuss the promising vaccines and treatment options for COVID-19, their challenges, and potential alternative strategies.",

keywords = "COVID-19, Convalescent plasma, Drug repurposing, SARS-CoV-2, Stem cell therapy, Vaccine interventions",

author = "Singh, {Vipul K.} and Abhishek Mishra and Shubhra Singh and Premranjan Kumar and Manisha Singh and Chinnaswamy Jagannath and Arshad Khan",

note = "Publisher Copyright: {\textcopyright} 2020 by the authors.",

year = "2020",

month = jun,

doi = "10.3390/pathogens9060501",

language = "English (US)",

volume = "9",

pages = "1--16",

journal = "Pathogens",

issn = "2076-0817",

publisher = "MDPI AG",

number = "6",

}

TY - JOUR

T1 - Emerging prevention and treatment strategies to control COVID-19

AU - Singh, Vipul K.

AU - Mishra, Abhishek

AU - Singh, Shubhra

AU - Kumar, Premranjan

AU - Singh, Manisha

AU - Jagannath, Chinnaswamy

AU - Khan, Arshad

PY - 2020/6

Y1 - 2020/6

N2 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has now become a serious global threat after inflicting more than 8 million infections and 425,000 deaths in less than 6 months. Currently, no definitive treatment or prevention therapy exists for COVID-19. The unprecedented rise of this pandemic has rapidly fueled research efforts to discover and develop new vaccines and treatment strategies against this novel coronavirus. While hundreds of vaccines/therapeutics are still in the preclinical or early stage of clinical development, a few of them have shown promising results in controlling the infection. Here, in this review, we discuss the promising vaccines and treatment options for COVID-19, their challenges, and potential alternative strategies.

AB - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has now become a serious global threat after inflicting more than 8 million infections and 425,000 deaths in less than 6 months. Currently, no definitive treatment or prevention therapy exists for COVID-19. The unprecedented rise of this pandemic has rapidly fueled research efforts to discover and develop new vaccines and treatment strategies against this novel coronavirus. While hundreds of vaccines/therapeutics are still in the preclinical or early stage of clinical development, a few of them have shown promising results in controlling the infection. Here, in this review, we discuss the promising vaccines and treatment options for COVID-19, their challenges, and potential alternative strategies.

KW - COVID-19

KW - Convalescent plasma

KW - Drug repurposing

KW - SARS-CoV-2

KW - Stem cell therapy

KW - Vaccine interventions

UR - http://www.scopus.com/inward/record.url?scp=85087053661&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85087053661&partnerID=8YFLogxK

U2 - 10.3390/pathogens9060501

DO - 10.3390/pathogens9060501

M3 - Review article

C2 - 32585805

AN - SCOPUS:85087053661

SN - 2076-0817

VL - 9

SP - 1

EP - 16

JO - Pathogens

JF - Pathogens

IS - 6

M1 - 501

ER -

Emerging prevention and treatment strategies to control COVID-19

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this