Emerging role of mini-host models in the study of aspergillosis

Georgios Chamilos; Dimitrios P. Kontoyiannis

doi:10.1201/9781420008517

Emerging role of mini-host models in the study of aspergillosis

Georgios Chamilos, Dimitrios P. Kontoyiannis

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

24.1 Introduction In recent years, opportunistic fungi have emerged as leading causes of morbidity and mortality in immunocompromised individuals [1,2]. The epidemiology of invasive fungal infections has evolved over the past two decades, partially because of the widespread use of antifungal agents with good activity against Candida, such as fluconazole. Since the early 1990s, ubiquitous airborne saprophytic molds have become the leading fungal pathogens in severely immunocompromised patients [1]. Aspergillus is the most common of these molds, and invasive aspergillosis (IA) has emerged as the major problem of modern mycology [2].

Original language	English (US)
Title of host publication	The Aspergilli
Subtitle of host publication	Genomics, Medical Aspects, Biotechnology, and Research Methods
Publisher	CRC Press
Pages	413-426
Number of pages	14
ISBN (Electronic)	9781420008517
ISBN (Print)	9780849390807
DOIs	https://doi.org/10.1201/9781420008517
State	Published - Jan 1 2007
Externally published	Yes

ASJC Scopus subject areas

General Agricultural and Biological Sciences
General Biochemistry, Genetics and Molecular Biology
General Immunology and Microbiology

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10.1201/9781420008517

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AB - 24.1 Introduction In recent years, opportunistic fungi have emerged as leading causes of morbidity and mortality in immunocompromised individuals [1,2]. The epidemiology of invasive fungal infections has evolved over the past two decades, partially because of the widespread use of antifungal agents with good activity against Candida, such as fluconazole. Since the early 1990s, ubiquitous airborne saprophytic molds have become the leading fungal pathogens in severely immunocompromised patients [1]. Aspergillus is the most common of these molds, and invasive aspergillosis (IA) has emerged as the major problem of modern mycology [2].

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Emerging role of mini-host models in the study of aspergillosis

Abstract

ASJC Scopus subject areas

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