Emerging strategies for cancer immunoprevention

J. C. Roeser; S. D. Leach; F. McAllister

doi:10.1038/onc.2015.98

Emerging strategies for cancer immunoprevention

J. C. Roeser, S. D. Leach, F. McAllister

Clinical Cancer Prevention

Research output: Contribution to journal › Review article › peer-review

39 Scopus citations

Abstract

The crucial role of the immune system in the formation and progression of tumors has been widely accepted. On one hand, the surveillance role of the immune system plays an important role in endogenous tumor prevention, but on the other hand, in some special circumstances such as in chronic inflammation, the immune system can actually contribute to the formation and progression of tumors. In recent years, there has been an explosion of novel targeted immunotherapies for advanced cancers. In the present manuscript, we explore known and potential various types of cancer prevention strategies and focus on nonvaccine-based cancer preventive strategies targeting the immune system at the early stages of tumorigenesis.

Original language	English (US)
Pages (from-to)	6029-6039
Number of pages	11
Journal	Oncogene
Volume	34
Issue number	50
DOIs	https://doi.org/10.1038/onc.2015.98
State	Published - Dec 10 2015

ASJC Scopus subject areas

Molecular Biology
Genetics
Cancer Research

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title = "Emerging strategies for cancer immunoprevention",

abstract = "The crucial role of the immune system in the formation and progression of tumors has been widely accepted. On one hand, the surveillance role of the immune system plays an important role in endogenous tumor prevention, but on the other hand, in some special circumstances such as in chronic inflammation, the immune system can actually contribute to the formation and progression of tumors. In recent years, there has been an explosion of novel targeted immunotherapies for advanced cancers. In the present manuscript, we explore known and potential various types of cancer prevention strategies and focus on nonvaccine-based cancer preventive strategies targeting the immune system at the early stages of tumorigenesis.",

author = "Roeser, {J. C.} and Leach, {S. D.} and F. McAllister",

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Emerging strategies for cancer immunoprevention

Abstract

ASJC Scopus subject areas

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