Endoscopic Management of High-Grade Dysplasia and Superficial Esophageal Carcinoma

Wayne L. Hofstetter; Raquel E. Davila; Marta L. Davila

doi:10.1016/B978-0-323-40232-3.00037-6

Endoscopic Management of High-Grade Dysplasia and Superficial Esophageal Carcinoma

Wayne L. Hofstetter, Raquel E. Davila, Marta L. Davila

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Esophagectomy is no longer considered standard therapy for high-grade dysplasia and early esophageal cancer limited to the mucosa. Organ-sparing procedures including endoscopic resection in combination with various forms of ablation have been shown to be the preferable option for the treatment of early esophageal neoplasia in most cases. This chapter will discuss the data that have led to this paradigm shift in treatment, along with specifying ideal candidates for endoscopic therapies, current treatment modalities, clinical and safety outcomes, and specific management recommendations.

Original language	English (US)
Title of host publication	Shackelford's Surgery of the Alimentary Tract
Subtitle of host publication	2 Volume Set
Publisher	Elsevier
Pages	382-390
Number of pages	9
ISBN (Electronic)	9780323402323
ISBN (Print)	9780323531771
DOIs	https://doi.org/10.1016/B978-0-323-40232-3.00037-6
State	Published - Jan 1 2019

Keywords

Cryotherapy
Dysplasia
Early stage esophageal carcinoma
Endoscopic resection
Endoscopic treatment
Esophageal adenocarcinoma
Esophageal squamous cell carcinoma
Esophagectomy
Intramucosal cancer
Mucosal resection
Radiofrequency ablation

ASJC Scopus subject areas

General Medicine

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10.1016/B978-0-323-40232-3.00037-6

Cite this

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title = "Endoscopic Management of High-Grade Dysplasia and Superficial Esophageal Carcinoma",

abstract = "Esophagectomy is no longer considered standard therapy for high-grade dysplasia and early esophageal cancer limited to the mucosa. Organ-sparing procedures including endoscopic resection in combination with various forms of ablation have been shown to be the preferable option for the treatment of early esophageal neoplasia in most cases. This chapter will discuss the data that have led to this paradigm shift in treatment, along with specifying ideal candidates for endoscopic therapies, current treatment modalities, clinical and safety outcomes, and specific management recommendations.",

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KW - Dysplasia

KW - Early stage esophageal carcinoma

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KW - Endoscopic treatment

KW - Esophageal adenocarcinoma

KW - Esophageal squamous cell carcinoma

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KW - Intramucosal cancer

KW - Mucosal resection

KW - Radiofrequency ablation

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BT - Shackelford's Surgery of the Alimentary Tract

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ER -

Endoscopic Management of High-Grade Dysplasia and Superficial Esophageal Carcinoma

Abstract

Keywords

ASJC Scopus subject areas

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