TY - JOUR
T1 - Endoscopic ultrasound guided fine needle aspiration of malignant pancreatic lesions
AU - Bhutani, M. S.
AU - Hawes, R. H.
AU - Baron, P. L.
AU - Sanders-Cliette, A.
AU - Van Velse, A.
AU - Osborne, J. F.
AU - Hoffman, B. J.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1997/11
Y1 - 1997/11
N2 - Purpose: To evaluate the accuracy, safety, and clinical utility of endoscopic ultrasound (EUS) guided fine needle aspiration (FNA) of pancreatic masses. Methods: Forty-seven patients were referred for EUS with a pancreatic mass and suspicion of pancreatic cancer based upon painless obstructive jaundice, epigastric abdominal pain plus weight loss/anorexia, or idiopathic pancreatitis. All patients underwent EUS with both radial (Olympus UM20) and linear array (Pentax FG32-UA) systems. After TNM staging by EUS, ultrasound directed FNA of the pancreatic mass was performed using a 23 gauge, 4 cm long needle. Results: EUS-guided FNA was performed in all 47 patients. Results: successful targeting = 100%, adequate cellularity = 100%, Findings: adeno Ca = 25, squamous cell Ca = 1, lymphoma = 1, poorly differentiated Ca = 1, atypical cytology or suspicious for carcinoma = 9, no malignant cells = 10. The sensitivity, specificity, positive predictive value and negative predictive value of EUS-guided pancreatic FNA for the diagnosis of malignancy was 64%, 100%, 100% and 16% respectively. Conclusions: EUS with FNA is useful for detection of malignancy in a pancreatic mass. The procedure appears to have a complication rate of 2%. Impact of this technique on clinical management of patients needs further evaluation.
AB - Purpose: To evaluate the accuracy, safety, and clinical utility of endoscopic ultrasound (EUS) guided fine needle aspiration (FNA) of pancreatic masses. Methods: Forty-seven patients were referred for EUS with a pancreatic mass and suspicion of pancreatic cancer based upon painless obstructive jaundice, epigastric abdominal pain plus weight loss/anorexia, or idiopathic pancreatitis. All patients underwent EUS with both radial (Olympus UM20) and linear array (Pentax FG32-UA) systems. After TNM staging by EUS, ultrasound directed FNA of the pancreatic mass was performed using a 23 gauge, 4 cm long needle. Results: EUS-guided FNA was performed in all 47 patients. Results: successful targeting = 100%, adequate cellularity = 100%, Findings: adeno Ca = 25, squamous cell Ca = 1, lymphoma = 1, poorly differentiated Ca = 1, atypical cytology or suspicious for carcinoma = 9, no malignant cells = 10. The sensitivity, specificity, positive predictive value and negative predictive value of EUS-guided pancreatic FNA for the diagnosis of malignancy was 64%, 100%, 100% and 16% respectively. Conclusions: EUS with FNA is useful for detection of malignancy in a pancreatic mass. The procedure appears to have a complication rate of 2%. Impact of this technique on clinical management of patients needs further evaluation.
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U2 - 10.1055/s-2007-1004321
DO - 10.1055/s-2007-1004321
M3 - Article
C2 - 9476770
AN - SCOPUS:0031466116
SN - 0013-726X
VL - 29
SP - 854
EP - 858
JO - Endoscopy
JF - Endoscopy
IS - 9
ER -