Abstract
Background: The purpose of this study was to assess the utility of imaging and endoscopy in posttreatment surveillance of sinonasal malignancies. Methods: We conducted a retrospective analysis of primary sinonasal malignancies diagnosed between 2000 and 2014. Posttreatment surveillance included nasal endoscopy and imaging (MRI, CT, and positron emission tomography [PET]/CT). Positive predictive value (PPV), negative predictive value (NPV), specificity, and sensitivity were calculated for each modality and compared. Results: One hundred nine sinonasal malignancies were identified with 30 recurrences. Endoscopy showed a sensitivity and specificity of 24% and 89%, respectively, whereas imaging was 76% and 90%, respectively. Identifying suspicious symptoms significantly improved the PPV of both endoscopy and imaging. MRI demonstrates the highest PPV when compared with other imaging modalities. Conclusion: Both modalities are necessary in posttreatment surveillance. MRI shows the highest PPV, whereas endoscopy trends toward a higher specificity. PET/CT scans have a high false-positive rate and should be reserved for tumors with a high propensity for distant metastases.
Original language | English (US) |
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Pages (from-to) | 1229-1233 |
Number of pages | 5 |
Journal | Head and Neck |
Volume | 38 |
Issue number | 8 |
DOIs | |
State | Published - Aug 1 2016 |
Externally published | Yes |
Keywords
- endoscopy
- malignancy
- recurrence
- sinonasal
- surveillance
ASJC Scopus subject areas
- Otorhinolaryngology