Entamoeba

Nadia Flores-Huerta; Moisés Martínez-Castillo; Paula Guzmán-Téllez; Angélica Silva-Olivares; Gabriela Rosales-Morgan; Judith Pacheco-Yépez; Mireya de la Garza; Jesús Serrano-Luna; Mineko Shibayama

doi:10.1016/B978-0-12-818619-0.00068-X

Entamoeba

Nadia Flores-Huerta, Moisés Martínez-Castillo, Paula Guzmán-Téllez, Angélica Silva-Olivares, Gabriela Rosales-Morgan, Judith Pacheco-Yépez, Mireya de la Garza, Jesús Serrano-Luna, Mineko Shibayama

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The genus Entamoeba covers several amoebae that reside mainly in the human gastrointestinal tract, of which Entamoeba histolytica is responsible for causing intestinal amebiasis (IA) and amoebic liver abscess (ALA) in humans, leading to annual deaths of 100,000 worldwide. Through adhesion, contact dependent-lysis, and phagocytosis, E. histolytica invades host tissue and provokes acute inflammatory reaction that underlines the key molecular pathogenesis of amebiasis. The diagnosis of E. histolytica infection involves microscopic examination, serological tests, and molecular techniques. Although antiamebic drugs are currently available, the emergence of multidrug resistance E. histolytica phenotypes calls for alternative therapeutic compounds and effective vaccines for ultimate control of this important parasite.

Original language	English (US)
Title of host publication	Molecular Medical Microbiology, Third Edition
Publisher	Elsevier
Pages	3069-3089
Number of pages	21
ISBN (Electronic)	9780128186190
DOIs	https://doi.org/10.1016/B978-0-12-818619-0.00068-X
State	Published - Jan 1 2023
Externally published	Yes

Keywords

amebiasis
diagnosis
Entamoeba
epidemiology
immunology
morphology
pathogenesis
pathophysiology
prevention
treatment

ASJC Scopus subject areas

General Immunology and Microbiology

Access to Document

10.1016/B978-0-12-818619-0.00068-X

Cite this

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title = "Entamoeba",

abstract = "The genus Entamoeba covers several amoebae that reside mainly in the human gastrointestinal tract, of which Entamoeba histolytica is responsible for causing intestinal amebiasis (IA) and amoebic liver abscess (ALA) in humans, leading to annual deaths of 100,000 worldwide. Through adhesion, contact dependent-lysis, and phagocytosis, E. histolytica invades host tissue and provokes acute inflammatory reaction that underlines the key molecular pathogenesis of amebiasis. The diagnosis of E. histolytica infection involves microscopic examination, serological tests, and molecular techniques. Although antiamebic drugs are currently available, the emergence of multidrug resistance E. histolytica phenotypes calls for alternative therapeutic compounds and effective vaccines for ultimate control of this important parasite.",

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author = "Nadia Flores-Huerta and Mois{\'e}s Mart{\'i}nez-Castillo and Paula Guzm{\'a}n-T{\'e}llez and Ang{\'e}lica Silva-Olivares and Gabriela Rosales-Morgan and Judith Pacheco-Y{\'e}pez and {de la Garza}, Mireya and Jes{\'u}s Serrano-Luna and Mineko Shibayama",

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doi = "10.1016/B978-0-12-818619-0.00068-X",

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AU - Flores-Huerta, Nadia

AU - Martínez-Castillo, Moisés

AU - Guzmán-Téllez, Paula

AU - Silva-Olivares, Angélica

AU - Rosales-Morgan, Gabriela

AU - Pacheco-Yépez, Judith

AU - de la Garza, Mireya

AU - Serrano-Luna, Jesús

AU - Shibayama, Mineko

PY - 2023/1/1

Y1 - 2023/1/1

N2 - The genus Entamoeba covers several amoebae that reside mainly in the human gastrointestinal tract, of which Entamoeba histolytica is responsible for causing intestinal amebiasis (IA) and amoebic liver abscess (ALA) in humans, leading to annual deaths of 100,000 worldwide. Through adhesion, contact dependent-lysis, and phagocytosis, E. histolytica invades host tissue and provokes acute inflammatory reaction that underlines the key molecular pathogenesis of amebiasis. The diagnosis of E. histolytica infection involves microscopic examination, serological tests, and molecular techniques. Although antiamebic drugs are currently available, the emergence of multidrug resistance E. histolytica phenotypes calls for alternative therapeutic compounds and effective vaccines for ultimate control of this important parasite.

AB - The genus Entamoeba covers several amoebae that reside mainly in the human gastrointestinal tract, of which Entamoeba histolytica is responsible for causing intestinal amebiasis (IA) and amoebic liver abscess (ALA) in humans, leading to annual deaths of 100,000 worldwide. Through adhesion, contact dependent-lysis, and phagocytosis, E. histolytica invades host tissue and provokes acute inflammatory reaction that underlines the key molecular pathogenesis of amebiasis. The diagnosis of E. histolytica infection involves microscopic examination, serological tests, and molecular techniques. Although antiamebic drugs are currently available, the emergence of multidrug resistance E. histolytica phenotypes calls for alternative therapeutic compounds and effective vaccines for ultimate control of this important parasite.

KW - amebiasis

KW - diagnosis

KW - Entamoeba

KW - epidemiology

KW - immunology

KW - morphology

KW - pathogenesis

KW - pathophysiology

KW - prevention

KW - treatment

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DO - 10.1016/B978-0-12-818619-0.00068-X

M3 - Chapter

AN - SCOPUS:85184331131

SP - 3069

EP - 3089

BT - Molecular Medical Microbiology, Third Edition

PB - Elsevier

ER -

Entamoeba

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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